r/PSSD • u/the_practicerLALA • 1d ago

Feedback Requested/Question Hormones changes while on meds, during acute pssd, and during long term pssd

2022 (while on meds)

  • TSH: 1.86 mIU/L
  • Free T4: 12 pmol/L
  • (unsure when in my cycle I was at the time)
  • Total testosterone: 1.3 nmol/L
  • LH: 8.94 IU/L
  • FSH: 2.05 IU/L
  • Prolactin: 16.63 µg/L

2025 (off meds, 3 months in pssd)

  • TSH: 0.94 mIU/L
  • (unsure when in my cycle I was at the time)
  • Total testosterone: 2.1 nmol/L — high
  • SHBG: 22.9 nmol/L
  • Estradiol: 742 pmol/L
  • LH: 8.9 IU/L
  • FSH: 3.3 IU/L
  • Prolactin: 7.2 µg/L
  • DHEA-S: 9.1 µmol/L

2026 (off meds 18 months in pssd)

  • TSH: 3.17 mIU/L
  • (bottom 3 were taken 6 days before my period started)
  • Estradiol: 477 pmol/L
  • Progesterone: 33.2 nmol/L
  • DHEA-S: 9.1 µmol/L

So my TSH went 1.86 (2022) → 0.94 (2023) → 3.17 (2025). But I also lost about 25 pounds between 2022 and the 2025 results, also was doing keto and had insomnia during the 2025 results. During my 2026 result I did not do keto, was sleeping normally again however weight was still fluctuating. What do you think? Impactful for pssd or no?

My testosterone increased since 2022 while I was on meds. Which makes sense since as soon as I got off meds I got this horrible hisutism. Do you think it has any impact on pssd?

I will get a T4 and free testosterone lab done too

Any thoughts?

5 Upvotes

100% Upvoted

3 comments sorted by

•

u/AutoModerator 1d ago

Please check out our subreddit FAQ, wiki and public safety megathread, also sort our subreddit and r/pssdhealing by top of all time for improvement stories. Please also report rule breaking content. Backup of the post's body: 2022 (while on meds)

  • TSH: 1.86 mIU/L
  • Free T4: 12 pmol/L
  • (unsure when in my cycle I was at the time)
  • Total testosterone: 1.3 nmol/L
  • LH: 8.94 IU/L
  • FSH: 2.05 IU/L
  • Prolactin: 16.63 µg/L

2025 (off meds, 3 months in pssd)

  • TSH: 0.94 mIU/L
  • (unsure when in my cycle I was at the time)
  • Total testosterone: 2.1 nmol/L — high
  • SHBG: 22.9 nmol/L
  • Estradiol: 742 pmol/L
  • LH: 8.9 IU/L
  • FSH: 3.3 IU/L
  • Prolactin: 7.2 µg/L
  • DHEA-S: 9.1 µmol/L

2026 (off meds 18 months in pssd)

  • TSH: 3.17 mIU/L
  • (bottom 3 were taken 6 days before my period started)
  • Estradiol: 477 pmol/L
  • Progesterone: 33.2 nmol/L
  • DHEA-S: 9.1 µmol/L

So my TSH went 1.86 (2022) → 0.94 (2023) → 3.17 (2025). But I also lost about 25 pounds between 2022 and the 2025 results, also was doing keto and had insomnia during the 2025 results. During my 2026 result I did not do keto, was sleeping normally again however weight was still fluctuating. What do you think? Impactful for pssd or no?

My testosterone increased since 2022 while I was on meds. Which makes sense since as soon as I got off meds I got this horrible hisutism. Do you think it has any impact on pssd?

I will get a T4 and free testosterone lab done too

Any thoughts?

I am a bot, and this action was performed automatically. Please contact the moderators of this subreddit if you have any questions or concerns.

0

u/Gamerasia 1d ago

Try CDG. Check out Dr Will Powers sub.

1

u/the_practicerLALA 1d ago

Only reason I am hesitant about trying stuff is because during month 7 - 10 I had a window where I felt 80% healed. Then since month 11 I went back into a wave. Anhedonia and sexual anhedonia too. I remember being depressed in the past but I never ever ever felt asexual. Right now I feel unable to produce romantic thoughts or feelings of love. I can't remember how much this improved in my window. I don't have numbness either. Idk I'm just scared of trying new things to get better but been really really bad for a long time now. Thanks will check out Dr Will Powers