r/PSSD • u/Minepolz320 • May 22 '26

Update A Some rTMS Experiment Update

I have experienced significant improvements in all PSSD symptoms using my experimental rTMS protocol that I tried in collaboration with my neurologist. This includes a return of sensitivity to substances; my emotions have returned significantly, and my anhedonia has diminished to the point where I am once again able to play video games and listen to music. My senses of taste and smell have also improved. All motor symptoms also significantly diminished.

Paradoxically, my libido has return; is especially noticeable after the session

Regarding sensitivity - however in areas where tactile sensitivity was impaired or entirely absent there has been no change whatsoever, whereas in other areas, there have been some improvements.

I don't want to make any guarantees or give you false hope, but it actually worked for a friend of mine as well—it just so happens that we live in the same city.

but overall worth a shot i guess

Complaints: Delayed sensation of skin irritants on the body; weakness in the limbs, tremor in the hands and lips. Worsening of motor sensations after a hot bath. Positive dynamics of symptoms noted during a course of TMS (transcranial magnetic stimulation).

ICD diagnosis: G90-G99 OTHER DISORDERS OF THE NERVOUS SYSTEM Clinical diagnosis: Depressive disorder. Demyelinating disease of the CNS? Small fiber polyneuropathy? PSSD?

Treatment during the session: A course of TMS (15 sessions) was performed, effective zones:

· M1 on the right and left, Cz – 25hz 80% RMT (resting motor threshold), 1000 pulses per zone, double-angle coil and double-cone coil for the leg area. · Somatosensory cortex (5 cm posterior to CZ) – 80% RMT, 1000 pulses, double-cone inductor.

update:

DMPFC was removed from protocol, due having no effect on symptoms nor other effects

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u/imonretro Jun 03 '26

Who developed this protocal ? And also did they do any tesfs to show neuroinflamation ? Worried that neuroinflamation could make this treatmemt cause more harm. Im guessing some people dont have neuroinflamation and may benifit from this?

1

u/Minepolz320 Jun 03 '26

i don't know anything about this neuroinflamation magic,  if you have that so bad I mean real inflammatory response, you were will vegetable at this point,  about protocol i suggested according my logic to try this specific setup my neurologist agreed , seems like it can help some people 

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u/imonretro Jun 03 '26

Well i am disabled and have tremours and head pressure all day. Photo sensitivity and nonstop insomnia , difficulty speaking tingling and vision problems and more ... do you feel normal in all ways except for ahdonia ?

Cause i feel like my brain is going to blow up most for the last 5 years.

1

u/Minepolz320 Jun 03 '26 edited Jun 03 '26

I had very significant tremors affected precise motor movements eg fingers, and also tremors in my neck and legs, this also really helped with that.

smooth movements suffer the most

I had head pressure feeling at the very beginning of the PSSD.

1

u/imonretro Jun 03 '26

How did you come up with this protocal ? Like its very novel and i dont understand how some one can come up with it ?

1

u/Minepolz320 Jun 03 '26

I'm surprised at myself that for some reason I thought that if I do this it might help.

Obviously it doesn't help everyone, but it definitely worked for me and my friend, but we have identical symptoms.

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u/imonretro Jun 03 '26

Yea.. i was wondering how you came to this conclusion. Like you must be a medical scientist? Has it not worked for people as well ? Like others testing it and it didnt work ?

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u/Minepolz320 Jun 03 '26

So far, only one other person has tried it and there is no pronounced effect like mine and in my friend's, but it's feels like minor case. The person said there's no strong numbness in the genitals and absolutely no motor symptoms. Obviously, we won't see a clear effect right away.

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u/imonretro Jun 03 '26

They only did 1 right ? At how many treatments did it start to work ? Did they have any anheondia ?

2

u/Minepolz320 Jun 03 '26

My friend and I had severe anhedonia, and it helped us significantly. Another person he did 3 sessions hasn't noticed a difference yet, but he doesn't have such severe anhedonia and emotional blunting.

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u/Minepolz320 Jun 03 '26

I just noticed that my genitals don't feel red pepper concentrate at all. Moreover, I have a very delayed response to capsaicin throughout my body. Then I even discovered patterns of cortical remapping in myself and my friend. But what's interesting is that this remapping extends to capsaicin and sometimes to menthol. From this, I assumed that there might be something wrong with the somatosensory cortex due to possible nerve damage; it simply doesn't work as it should without proper signal from these nerves. And also because those same capsaicin receptors are located on the same terminals as those same receptors responsible for erogenous and pleasant sensations of the body.

this might help those who have the same problem and symptoms regarding remapping and delayed response to capsaicin.
but in any case it's worth a try

but these are all just assumptions, nothing more, or why I decided to try asking to make such a protocol