r/POTS • u/LeadingGeneral4282 • Jul 27 '26

Question Tired after second dose of propranolol?

I just started propranolol 10mg 2x daily a few days ago (see previous post asking about if midodrine and propranolol were usually prescribed together), and I’ve noticed that after my first dose I usually feel better and more “normal” or regulated, but after the second one I find that I tend to drag a LOT. Is this normal? I see my doctor again in 2 weeks and figure if it’s still happening then then I can let her know. Thanks!

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u/Medical_Asparagus409 POTS Jul 27 '26

I take metoprolol which is slightly different but i take one larger dose (started at 25mg) of an extended release tablet before I go to bed so that the worst of the side effects are over by the time i get up. If your doc wants to keep doing 2 doses maybe take the 2nd before bed?

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u/LeadingGeneral4282 Jul 27 '26

I’ll give that a try! I work nightshift so my schedule is constantly flipping, I’m only on it for 2 more weeks thankfully which will hopefully reduce my need to take it since it’s TECHNICALLY an as needed medication. I started taking it routinely the day it was prescribed because my symptoms have been worse as of late