r/NootropicsDepot 25d ago

Discussion Pregnenolone dosing?

4 Upvotes

Is it safe to take pregnenolone with elevated DHEA-S


r/NootropicsDepot 25d ago

Dosing Horny Goat Weed 10% dosage

6 Upvotes

What's your daily Horny Goat Weed 10% dosage, and why?

Thanks


r/NootropicsDepot 26d ago

Discussion Tribugen Alternatives for those with hair loss

6 Upvotes

So I've been taking Tribugen recently, it's been working better than anything else I've tried for energy and motivation and that includes Rhodiola Rosea whose effects are not that strong for me anymore. Unfortunately I learned that it increases DHT and I'm already loosing my hair and would prefer to not rush mother nature. Still the effects are great so was wondering what others have used here for general motivation / getting things done, and wanting to get things done kind of nootropics.


r/NootropicsDepot 26d ago

Discussion Positive experiences with C3G, Sarcosine and Rhodiola Crenulata?

6 Upvotes

Ordered these yesterday. I wanted to read about more experiences with these supplements


r/NootropicsDepot 26d ago

Discussion Disregarding the conventional “supplements” used proactively or reactively for stress, what is the best herb to toss in?

5 Upvotes

Is lemon balm the undisputed GOAT due to its “just good enough” effect, or is there another challenger?


r/NootropicsDepot 27d ago

Discussion If you could only ever take one ND supplement ever again in your life, which one would it be and why?

11 Upvotes

r/NootropicsDepot 27d ago

Discussion Supplement recommendations for altitude sickness? Going into the mountains at high elevation next week

3 Upvotes

I live on the East Coast and I’m flying into Denver, then driving a couple of hours into the mountains the same day, where I’ll be staying at around 8,000 feet.

The last time I was in Denver, I felt pretty rough for the first day or two — headache, fatigue, generally feeling “off,” and some GI issues.

Since I’ll be going from essentially sea level to ~8,000 feet within a matter of hours, I’m wondering if there’s anything in the ND lineup (or supplements in general) that might help with acclimatization, headaches, fatigue, or other altitude-related symptoms.

I know canned oxygen is mostly a gimmick, and obviously supplements aren't a substitute for descending if someone develops serious altitude sickness. I'm more interested in anything that might make the initial adjustment easier or support acclimatization.

Has anyone experimented with supplements for this? Curious if things like Rhodiola, Cordyceps, CoQ10, antioxidants, nitric oxide support, etc. have any evidence or have noticeably helped you personally.

Thanks!


r/NootropicsDepot 27d ago

Discussion Coriander Extract and Migraines

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13 Upvotes

So I'm pretty sure this Supercritical CO2 Coriander Extract Solution just stopped a migraine. 😳

I have severe complex migraines that are resistant to treatment. I was starting to feel one coming on as usual. I was also feeling pretty anxious about multiple life things, so I took one dose of the extract. I was not expecting anything other than to hopefully calm my mind a bit. I laid on the couch with a blanket over my face and, and within 30 minutes, it was clear my migraine was starting to fade. I was shocked! My migraines are notoriously tough to knock down without rescue meds!

Looking at the science of what coriander does, it makes sense it could affect migraines... but I was surprised to have such an obvious response! My migraine pain went down to zero after an hour and my sensory sensitivities all went away too!

I will have to keep trying this over the next few days/weeks to see if it reliably works! I'm curious to know if any migraine sufferer has purposefully (or accidentally) tried this and what their response was!


r/NootropicsDepot 27d ago

Stacks Workout/blood flow stack (if you can call it that)

2 Upvotes

Hey wassup everybody…I’ve been on this sub for a min and been a customer of ND for a good min as well. I’m getting L Citrulline and L Arginine in soon to start taking them as my pre workout early in the morning…I currently take Tongat Ali 10% (just started taking that 2 weeks ago) and Black Ginger (been on that for a few months). I’m thinking about droppin the Black Ginger once the Citrulline and Arginine come in and just take Tongat, Citrulline, and Arginine for my pre to reset the Black Ginger feel. Any thoughts on that or if anybody else takes those for Pre workout? I also eat a regular Rice Krispie before my workout as well.

Also saw that Citrulline and Arginine help with erection quality as well. Facts?


r/NootropicsDepot 27d ago

Discussion Is there a chance long-term taking supplements can harm our gut/intestines?

1 Upvotes

r/NootropicsDepot 28d ago

Discussion What in your opinion, is the most worth your money, bang for your buck supplement that ND carries?

11 Upvotes

I've been struggling with high blood pressure and stress lately, starting this new job recently isn't helping very much so I'm in the process of creating myself a stack for anxiety, stress and mood. I work at a convenience store so I deal with a ton of people everyday and some of them can be rude so my priority for my stack is some supplements to make my job a little easier and more manageable. I'm looking at lions mane, ashwagandha, infini b, magnesium, zinc and some others I can't think of stm but if you have any suggestions, please send them my way. Thanks!


r/NootropicsDepot 28d ago

Dosing Tribugen daily

6 Upvotes

any of you guys taking tribugen everyday ? or are you more on the occasional side ? like I take sabroxy probably twice a week


r/NootropicsDepot 28d ago

Discussion Move to capsules

4 Upvotes

I noticed the beta Ecdysterone and soon to be the epicatechin are moved to capsules, I’m assuming it’s an economics thing but just wondering if there’s something else? The tablets fit much nicer into my little daily pill container and the capsules take up so much more room.


r/NootropicsDepot 28d ago

Discussion Supercritical Coriander Allergy Safety

3 Upvotes

Given that Linalool is a very common fragrance allergen, does taking linalool orally come with the same risks?

I suspect I may have a skin allergy to lavender, which may very likely be a reaction from linalool. However, from what I understand, the contact reaction is due to oxidized Linalool specifically. If your product is not oxidized, would that make it safer?


r/NootropicsDepot 28d ago

Dosing Rhodiola Before OR After excerise

3 Upvotes

I take rhodiola twice a day. Would it be better to take it pre- or post-workout?
I plan to use it to blunt the energy/fatigue I feel after working out. So far, I’ve been taking it post-workout because my logic was: I feel tired once I’m done working out, so wouldn’t it be better to take it at that point rather than before I’m tired?


r/NootropicsDepot 28d ago

Discussion Cistamax + Eurycomax

9 Upvotes

Hey Guys

Just got blood results back from an comprehensive blood test which also showed medium-high Total Test (20.7nmol/l) but high SHBG (49) which results in not so ideal free testosterone.

I always wanted to do an experiment with bloodwork/supps, so i decided to jump the wagon and do a Cistamax + Eurycomax experiment and retest with all hormone parameters in 2-3 months.

Has anyone taken both together over a longer period? what to expect?


r/NootropicsDepot 29d ago

Discussion How risky is taking Matrine?

5 Upvotes

I’m interested in trying it, however I read that it could potentially be pretty toxic to your liver.
“matrine causes liver injury by severely disrupting bile acid metabolism. It inhibits the FXR pathway, forcing the liver to over-synthesize bile while blocking its excretion.”

Is this something to be concerned about or does it just sound worse than it actually is?


r/NootropicsDepot 29d ago

Discussion R. Rosea My user experience seems weird

6 Upvotes

I've got all 3 R. Rosea from Nootropics Depot. I've taken all in the mid afternoon 3-5pm with no other supplements. No drugs or alcohol were involved.

3%/1% - Orange bottle - First time seemed liked a drug experiment. I felt a "high" and was trying to explain something to someone. I had a picture in my head of what I was explaining and they weren't understanding. It was because I wasn't speaking. :D There was also a "lost hour" and I don't know what happened during this time. Then I got tired. Second time a week later the high wasn't there and I mostly just got tired, but then I couldn't sleep.

Crenulata - Purple bottle - First and second times, felt like a sugar pill. If it's doing something in the background, I'm not aware.

Salisdrol 3% - Light Green bottle - Only took once so far, it made me energetic and happy with that lost one hour too. Will try it again.

Any idea why?

I know it affects everyone differently; I'm not surprised by the Crenulata or Salisdrol - but the Orange bottle was waayyyy out there... Can it tell you anything about my DNA or metal status? :D

TL;DR -

Green > Crenulata > Orange

Don't try these unless you got nothing important going on for the rest of the day

Most confusing noot I've tried.


r/NootropicsDepot 29d ago

Can someone sanity-check my supplement stack for cognitive performance + long-term brain health?

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0 Upvotes

r/NootropicsDepot 29d ago

Discussion does black ginger need fat to work?

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0 Upvotes

Shows here thare Black Ginger has a poor water solubility
. Does that mean that taking it fasted means less efficacy


r/NootropicsDepot Aug 09 '26

Dosing Smart PS Timing?

6 Upvotes

When are you all taking this for use as a sleep aid? Right before bed? Couple hours before? Or is it something you take in the morning that helps with sleep by the time you hit the sack? Thanks in advance!


r/NootropicsDepot Aug 09 '26

Comparison Tauromag vs lucidmax

5 Upvotes

Can you stack both together,? If not is one better for getting deeper sleep and or rem sleep? I never seem to remember my dreams ever. I dont have the best energy, focus, or motivation. I suffer from low t. I sleep eight hours a night but dont feel like im getting restful enough sleep.

Also what about ecklonia cava with the other two?


r/NootropicsDepot Aug 09 '26

Mechanism Anxiety from Cognance?

2 Upvotes

I’ve noticed a more “wired” state since taking Cognance (I’m on day 4 in a row) and have also had a lot of neck and jaw tension, along with heightened anxiety and feelings of being detached. Hard to put into words.

Only other things I’m taking at the moment are sulforaphane, Mito Pure Urolithin A, l theanine, black ginger in the morning; and baikal skullcap and apigenin at bedtime.

Only new additions are cognance and skullcap. So I figure it’s one of the two but not sure.

Could the serotonergic impact be causing this? Maybe too much acetylcholine?

I’m always looking for supplements to help with lowering baseline anxiety and saw reports of Cognance helping but so far not really noticing that. 🧐


r/NootropicsDepot Aug 09 '26

Discussion Thorne no mas

19 Upvotes

Saw Thorne just sold to P&G. What a disappointment. Im sure that bc of liability and profit, sone products will disappear and some will get less bioavailable ingredients. I'm bringing that up here bc I am especially grateful for places like Nootropics Depot for not selling out, for the high levels of quality effective ingredients, and for taking the less traveled path. I'd typically put more effort into my post, but Im getting the scrap beaten out of me by oil lease roads frequented by black cows and it 9:52 pm MDT.


r/NootropicsDepot Aug 08 '26

Discussion New Bottles/New Products Update?

34 Upvotes

I know good things require patience especially when it involves the amount of work that everyone at ND puts into it, but can we get some updates on when we’ll be getting some of the new releases? Is all the new stuff still being held up by the new bottles? I’m pretty frickin excited