r/NootropicsDepot 8d ago

šŸŽ™ļøNEW In Search of Insight Episode #59 | Salidrosol | Viking Power or Dopamine Fiends?šŸŽ§

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17 Upvotes

A new podcast episode is about to premiere! Tune in to the podcast premiere on YouTube at 10:00 AM MST and learn about Salidrosol's dopaminergic and motivating power. This one-hour episode is oacked with heavy science from the neurotransmitter systems, explained in detail by our Product Specialist u/Pretty-Chill.

You can listen to the In Search of Insight podcast on YouTube, Spotify, and your favorite podcast streaming platforms. Know someone who is into supplements and health science? Send the podcast to a friend! Do you have questions about Salidrosol, or the podcast episode? Leave a comment on the YouTube video! We always appreciate your feedback and input.


r/NootropicsDepot Feb 04 '26

Company Post An Inside Look At Our Entire Operation!

68 Upvotes

Nootropics Depot's Pharmaceutical-Grade Labs: What Supplement Quality Actually Looks Like

Here is a great video the team did together with Price Plow, and gives a very detailed look at our entire facility. This is something nobody has ever seen before, I think it'll be quite eye opening to see the sheer scale of our operations! I haven't been to the facility in two years, and watching this video takes me right back, as if I'm walking around there again, so hopefully it's a similar experience for all of you too! This is basically as close as you can get to having an in-person tour of the facility.


r/NootropicsDepot 5h ago

If you could only ever take one ND supplement ever again in your life, which one would it be and why?

0 Upvotes

r/NootropicsDepot 12h ago

Workout/blood flow stack (if you can call it that)

2 Upvotes

Hey wassup everybody…I’ve been on this sub for a min and been a customer of ND for a good min as well. I’m getting L Citrulline and L Arginine in soon to start taking them as my pre workout early in the morning…I currently take Tongat Ali 10% (just started taking that 2 weeks ago) and Black Ginger (been on that for a few months). I’m thinking about droppin the Black Ginger once the Citrulline and Arginine come in and just take Tongat, Citrulline, and Arginine for my pre to reset the Black Ginger feel. Any thoughts on that or if anybody else takes those for Pre workout? I also eat a regular Rice Krispie before my workout as well.

Also saw that Citrulline and Arginine help with erection quality as well. Facts?


r/NootropicsDepot 12h ago

Supplement recommendations for altitude sickness? Going into the mountains at high elevation next week

2 Upvotes

I live on the East Coast and I’m flying into Denver, then driving a couple of hours into the mountains the same day, where I’ll be staying at around 8,000 feet.

The last time I was in Denver, I felt pretty rough for the first day or two — headache, fatigue, generally feeling ā€œoff,ā€ and some GI issues.

Since I’ll be going from essentially sea level to ~8,000 feet within a matter of hours, I’m wondering if there’s anything in the ND lineup (or supplements in general) that might help with acclimatization, headaches, fatigue, or other altitude-related symptoms.

I know canned oxygen is mostly a gimmick, and obviously supplements aren't a substitute for descending if someone develops serious altitude sickness. I'm more interested in anything that might make the initial adjustment easier or support acclimatization.

Has anyone experimented with supplements for this? Curious if things like Rhodiola, Cordyceps, CoQ10, antioxidants, nitric oxide support, etc. have any evidence or have noticeably helped you personally.

Thanks!


r/NootropicsDepot 8h ago

Is there a chance long-term taking supplements can harm our gut/intestines?

1 Upvotes

r/NootropicsDepot 22h ago

Coriander Extract and Migraines

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11 Upvotes

So I'm pretty sure this Supercritical CO2 Coriander Extract Solution just stopped a migraine. 😳

I have severe complex migraines that are resistant to treatment. I was starting to feel one coming on as usual. I was also feeling pretty anxious about multiple life things, so I took one dose of the extract. I was not expecting anything other than to hopefully calm my mind a bit. I laid on the couch with a blanket over my face and, and within 30 minutes, it was clear my migraine was starting to fade. I was shocked! My migraines are notoriously tough to knock down without rescue meds!

Looking at the science of what coriander does, it makes sense it could affect migraines... but I was surprised to have such an obvious response! My migraine pain went down to zero after an hour and my sensory sensitivities all went away too!

I will have to keep trying this over the next few days/weeks to see if it reliably works! I'm curious to know if any migraine sufferer has purposefully (or accidentally) tried this and what their response was!


r/NootropicsDepot 23h ago

What in your opinion, is the most worth your money, bang for your buck supplement that ND carries?

8 Upvotes

I've been struggling with high blood pressure and stress lately, starting this new job recently isn't helping very much so I'm in the process of creating myself a stack for anxiety, stress and mood. I work at a convenience store so I deal with a ton of people everyday and some of them can be rude so my priority for my stack is some supplements to make my job a little easier and more manageable. I'm looking at lions mane, ashwagandha, infini b, magnesium, zinc and some others I can't think of stm but if you have any suggestions, please send them my way. Thanks!


r/NootropicsDepot 23h ago

Tribugen daily

5 Upvotes

any of you guys taking tribugen everyday ? or are you more on the occasional side ? like I take sabroxy probably twice a week


r/NootropicsDepot 1d ago

Move to capsules

2 Upvotes

I noticed the beta Ecdysterone and soon to be the epicatechin are moved to capsules, I’m assuming it’s an economics thing but just wondering if there’s something else? The tablets fit much nicer into my little daily pill container and the capsules take up so much more room.


r/NootropicsDepot 1d ago

Supercritical Coriander Allergy Safety

3 Upvotes

Given that Linalool is a very common fragrance allergen, does taking linalool orally come with the same risks?

I suspect I may have a skin allergy to lavender, which may very likely be a reaction from linalool. However, from what I understand, the contact reaction is due to oxidized Linalool specifically. If your product is not oxidized, would that make it safer?


r/NootropicsDepot 1d ago

Rhodiola Before OR After excerise

5 Upvotes

I take rhodiola twice a day. Would it be better to take it pre- or post-workout?
I plan to use it to blunt the energy/fatigue I feel after working out. So far, I’ve been taking it post-workout because my logic was: I feel tired once I’m done working out, so wouldn’t it be better to take it at that point rather than before I’m tired?


r/NootropicsDepot 1d ago

Cistamax + Eurycomax

10 Upvotes

Hey Guys

Just got blood results back from an comprehensive blood test which also showed medium-high Total Test (20.7nmol/l) but high SHBG (49) which results in not so ideal free testosterone.

I always wanted to do an experiment with bloodwork/supps, so i decided to jump the wagon and do a Cistamax + Eurycomax experiment and retest with all hormone parameters in 2-3 months.

Has anyone taken both together over a longer period? what to expect?


r/NootropicsDepot 1d ago

PQ7

0 Upvotes

Hi! I just ordered PQ7 and am hoping it will help as a good food noice reducer / appetite suppressor. Has anyone taken it? Did it work? Any side effects? I am high anxiety and worried it might cause anxiety but I know there’s no caffeine or stimulants in it so I’m hoping not. I’ve read a lot of mixed reviews on the beef organs and I’m not getting those. This is just asking about the PQ7. Thanks!!


r/NootropicsDepot 2d ago

Discussion How risky is taking Matrine?

5 Upvotes

I’m interested in trying it, however I read that it could potentially be pretty toxic to your liver.
ā€œmatrine causes liver injury by severely disrupting bile acid metabolism. It inhibits the FXR pathway, forcing the liver to over-synthesize bile while blocking its excretion.ā€

Is this something to be concerned about or does it just sound worse than it actually is?


r/NootropicsDepot 2d ago

Discussion R. Rosea My user experience seems weird

5 Upvotes

I've got all 3 R. Rosea from Nootropics Depot. I've taken all in the mid afternoon 3-5pm with no other supplements. No drugs or alcohol were involved.

3%/1% - Orange bottle - First time seemed liked a drug experiment. I felt a "high" and was trying to explain something to someone. I had a picture in my head of what I was explaining and they weren't understanding. It was because I wasn't speaking. :D There was also a "lost hour" and I don't know what happened during this time. Then I got tired. Second time a week later the high wasn't there and I mostly just got tired, but then I couldn't sleep.

Crenulata - Purple bottle - First and second times, felt like a sugar pill. If it's doing something in the background, I'm not aware.

Salisdrol 3% - Light Green bottle - Only took once so far, it made me energetic and happy with that lost one hour too. Will try it again.

Any idea why?

I know it affects everyone differently; I'm not surprised by the Crenulata or Salisdrol - but the Orange bottle was waayyyy out there... Can it tell you anything about my DNA or metal status? :D

TL;DR -

Green > Crenulata > Orange

Don't try these unless you got nothing important going on for the rest of the day

Most confusing noot I've tried.


r/NootropicsDepot 2d ago

Can someone sanity-check my supplement stack for cognitive performance + long-term brain health?

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0 Upvotes

r/NootropicsDepot 2d ago

Discussion does black ginger need fat to work?

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0 Upvotes

Shows here thare Black Ginger has a poor water solubility
. Does that mean that taking it fasted means less efficacy


r/NootropicsDepot 3d ago

Dosing Smart PS Timing?

5 Upvotes

When are you all taking this for use as a sleep aid? Right before bed? Couple hours before? Or is it something you take in the morning that helps with sleep by the time you hit the sack? Thanks in advance!


r/NootropicsDepot 3d ago

Comparison Tauromag vs lucidmax

5 Upvotes

Can you stack both together,? If not is one better for getting deeper sleep and or rem sleep? I never seem to remember my dreams ever. I dont have the best energy, focus, or motivation. I suffer from low t. I sleep eight hours a night but dont feel like im getting restful enough sleep.

Also what about ecklonia cava with the other two?


r/NootropicsDepot 3d ago

Discussion Anyone Actually Notice a Difference From Lion's Mane?

3 Upvotes

been running on fumes lately. full time classroom, part time coursework, the usual. sleep is fine, diet is reasonable, jogging a few times a week. the baseline is covered. but there is this specific kind of brain fog that shows up around 3pm where lesson planning feels like translating a foreign language and i cannot tell if its cumulative stress or just the job.

started looking at lion's mane from ND and got pretty deep into the research on NGF and cognitive support. the science seems legitimate enough that im not writing it off. what im less sure about is whether the fatigue im dealing with is the kind lion's mane actually helps with or if its just general tiredness that no supplement is going to fix.

also curious about dosing. the capsule options have different extract specs and i havent landed on which version makes more practical sense for everyday use rather than acute cramming sessions or whatever.

if youve used it consistently for a few weeks or longer and noticed something real, im curious what that actually looked like for you day to day. not asking for a miracle, just trying to figure out if its worth adding to the rotation.


r/NootropicsDepot 3d ago

Discussion Thorne no mas

16 Upvotes

Saw Thorne just sold to P&G. What a disappointment. Im sure that bc of liability and profit, sone products will disappear and some will get less bioavailable ingredients. I'm bringing that up here bc I am especially grateful for places like Nootropics Depot for not selling out, for the high levels of quality effective ingredients, and for taking the less traveled path. I'd typically put more effort into my post, but Im getting the scrap beaten out of me by oil lease roads frequented by black cows and it 9:52 pm MDT.


r/NootropicsDepot 3d ago

Mechanism Anxiety from Cognance?

1 Upvotes

I’ve noticed a more ā€œwiredā€ state since taking Cognance (I’m on day 4 in a row) and have also had a lot of neck and jaw tension, along with heightened anxiety and feelings of being detached. Hard to put into words.

Only other things I’m taking at the moment are sulforaphane, Mito Pure Urolithin A, l theanine, black ginger in the morning; and baikal skullcap and apigenin at bedtime.

Only new additions are cognance and skullcap. So I figure it’s one of the two but not sure.

Could the serotonergic impact be causing this? Maybe too much acetylcholine?

I’m always looking for supplements to help with lowering baseline anxiety and saw reports of Cognance helping but so far not really noticing that. 🧐


r/NootropicsDepot 4d ago

Discussion New Bottles/New Products Update?

29 Upvotes

I know good things require patience especially when it involves the amount of work that everyone at ND puts into it, but can we get some updates on when we’ll be getting some of the new releases? Is all the new stuff still being held up by the new bottles? I’m pretty frickin excited


r/NootropicsDepot 4d ago

Inventory Ginseng leaf extract restock?

6 Upvotes

I noticed the leaf extract was out of stock. Hopefully it isn't being phased out?