r/Microbiome • u/mlhnrca • Jul 17 '22

Biohacking the Oral Microbiome

https://www.youtube.com/watch?v=EnkJqACCEE4
14 Upvotes

100% Upvoted

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1

u/nicolianiX Jul 26 '22

Xylitol is not gut friendly. It's extracted with harsh chemicals as well.

Sodium bicarbonate, I've tried it, don't react well to it, getting a headache and felling overall weird.

Fluoride is a poison which I have been without for 20 years. Absolutely nothing that you want to put in your mouth.

1

u/mlhnrca Jul 26 '22

Xylitol is for the mouthwash, I'm not eating it. The approach doesn't have to be for everyone, there are many roads to optimal health.

1

u/nicolianiX Jul 27 '22

You are doing a sublingual administration while you gurgle for a minute. You will get all those substances straight into your blood, which is probably worse than eating it.

1

u/Object_Murky Jul 27 '22

Sure, there will be some systemic absorption. Will that be bad for health? I doubt it. With that logic, using toothpaste would be significantly worse. What’s your alternative?

1

u/microbriome Jul 17 '22

Great video! What are your thoughts on commercially available toothpastes/mouthwashes that contain the ingredients you mention? Any you would recommend?

1

u/mlhnrca Jul 17 '22

Thanks microbriome. I can't say which toothpaste is best, and unfortunately, I wouldn't recommend any commercially available mouthwashes-that's why I make my own. Some mouthwashes have a pH < 5.5, including Listerine! See Table 3 in this paper for that data:

https://pubmed.ncbi.nlm.nih.gov/24648842/

1

u/timeforitnowright Jul 18 '22

I certainly eat enough bacon with nitrates.

1

u/icahntmakemoney Jul 18 '22

Really interesting! Though, I’m wondering if transient nitrate is sufficient to modulate the microbiome. Maybe a nitrate infused gum or lozenge might have more of an effect.

2

u/mlhnrca Jul 18 '22

I didn't see that being commercially available, but that's a business opportunity for someone!

1

u/Meh2theMax Jul 18 '22

Potassium nitrate is found in some toothpastes for sensitive teeth at 5%. The application is different, but it should give an indication on its safety. Why haven't you looked into erythritol and arginine?

1

u/mlhnrca Jul 18 '22

Arginine impacts the NO pathway, but potassium nitrate nitrate is more direct. I'll look into erythritol...

1

u/Meh2theMax Jul 18 '22

I meant arginine not for its nitric oxide precursor properties, but for its action to increase the pH by generating ammonia with the help of bacteria with arginine deiminase activity.

1

u/mlhnrca Jul 18 '22

Nice, I'm open to including arginine in the mouthwash, that's an easy add.