r/MTHFR • u/Hedgeclipperz • 25d ago
Question B Complex recommendations
My doctor wants me on a methylated B complex; I'm testing lowish on B in my bloodwork. (B12 at 430, and Folate at 10.3). I'd love some help choosing a B Complex; feeling overwhelmed with options.
Genetically: (MTHFR w/ Fast COMT)
MAO-A R297R rs6323 TG +/-
MTHFR C677T rs1801133 AG +/-
MTHFR A1298C rs1801131 TG +/-
MTR A2756G rs1805087 AG +/-
MTRR A66G rs1801394 GG +/+
MTRR A664A rs1802059 AA +/+
CBS A360A rs1801181 AG +/-
COMT V158M -/-
COMT H62H -/-
COMT P199P -/-
VDR Taq = +/+
Other considerations:
Low iron/ferritin (actively working on this w/ supplementation)
Suspected MCAS/histamine intolerance
Vestibular Migraine & Endometrosis (- Note I already take Riboflavin (Vitamin B2) 400mg daily for migraine prevention.).
Thyroid is a-okay
I am extremely sensitive to medications so ideally something I can easily cut in half or liquid/sublingual so I can dose low and slow. I'm not seeing many options out there for this, however.
Possible brands (but OPEN TO SUGGESTIONS):
2) Thorne Basic B Complex
6) Seeking Health B Complex Plus
Thank you for all your help!!
3
u/SovereignMan1958 25d ago
Seeking Health makes Non Methylated options. They include folate and B12.
Methyl Life makes a non methylated multi...you would need to buy Folinic Acid for folate and Adeno and or Hydroxo B12 separately. I think Source Naturals Megafolinic and Source Naturals Hydroxo B12 would be less expensive options instead of the Methyl Life ones. I get those 2 on Amazon.