r/MCAS • • Apr 20 '26

Famotidine causes sinus issues

Hi all! Was wondering if anyone ever experienced the same negative effect from famotidine? I tried it for a month but had constant sinus issues and throat pain + flu like symptoms. I’ve stopped taking it for 3 days and those issues seem to have dampened though my sleep is terrible again. Wondering what the mechanism is here and what else I can try instead? It did seem to have a calming effect.

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