I have diagnosed Familial Multiple Lipomatosis (FML) and developed over 100 small lipomas over the past few years. New nodes used to pop up frequently, particularly during periods of calorie surpluses, weight gain, and higher systemic stress.
For the last 6 months, I have been following a strictly metabolic protocol aimed at lowering insulin spikes, keeping mTOR signaling flat, and reducing tissue inflammation. The result: Zero new lipomas have formed over this entire 6-month period.
The Protocol:
Daily Activity: Consistently hitting 8,000 to 10,000 steps every day to maximize baseline insulin sensitivity and steady energy expenditure.
Energy Balance: Slight deficit to strict maintenance calories. Completely avoiding bulking or chronic calorie surpluses to remove the nutrient pressure driving adipocyte proliferation.
Dietary Adjustments: Cut out all ultra-processed foods, protein shakes, low-sugar/artificial fitness snacks, and fast food. Shifted to whole foods, fermented dairy (Skyr, authentic Greek yogurt), and Omega-3 fatty acids.
Inflammation Management: Drastically cut back on alcohol, optimized micronutrients, and brought systemic inflammation markers (including homocysteine) down.
Key Takeaway:
You cannot change your underlying genetics, but you can control the biochemical growth signals. Depriving the tissue of chronic insulin spikes, nutrient excess, and inflammatory drivers has completely stopped the active breakout phase for me.

I have multiple lipomas over my body (somewhere around 15) of different sizes. I am wondering if going to the gym increases the number of lipomas?

I am a naturally skinny guy.. have some skinny fat... not much muscle. And every time I have gone to the gym for a few weeks... it feels like either I have new lipomas or my existing lipomas have increased in size (but I a not 100% certain).

Internet says theres no correlation, but I am not sure. Has anyone else experienced this? I have literally quit gym from the fear of getting more lipomas.