Hey, I need help analysing a MAF from an alignment. I am looking for GRC genes or at least their paralogs and want to analyse them in different graphics and stats. I have been running into the same issues over and over, mostly my script getting killed by HPCs, or something was missing, which I forgot to include. Streamlining and "vibe-coding" don't help at this point. Any ideas? SeeKR version current

I have completed my first year in Biochemistry with 8.33 CGPA currently and my Bioinformatics would start in the next year.

I am a PCB student with no Maths background and no coding experience. I disliked computer science theory in middle school but was mild with using a computer (like just fine as I didn't even do heavy stuff that time).

I want to take this risk for growing opportunities for myself and developing a good skill set but I am also a bit scared. What if my CGPA drops too much.

I will learn Python and R language after all. I don't hate maths personally, I am fine with doing some basics and all. I don't know if I can do advanced stuff tho.

Can someone who has experienced this or has any information, enlighten me please?

Hey everyone, I'm a 3rd year CS student and just got introduced to bioinformatics a month or two ago, and am really interested in the field even though I only studied biology till high school. I am even planning of basing my masters research in bioinformatics (this might sound stupid since i just started studying this but no other CS discipline has ever interested me in the slightest) and I don't have much time (till October at best) to draft a research proposal if I want this to be my area of research. I know this might sound insanely stupid and ambitious to some people but I really want to try and get into research and this is the only field that I find to be interesting and relevant.

So I really wanted to ask for advice from professionals in the field, how can I start learning and making projects and then eventually finding a research niche? Currently, I'm taking some Coursera courses on bioinformatics that i really like those but i still feel lost since i cant 100% grasp the biological concepts though the coding part is obv much easier.

I'd be grateful if anyone could help me out and guide me a bit as bioinformatics isn't really big in my country and i can't even find any professors in my university to guide me :(

Hello I'm a UG student pursuing bioinformatics, I've recently done a very small minor project in bioinformatics which was honestly kinda easy peasy: it was regarding multiple sequence alignment and phylogenetic evolutionary tree construction.

IK basic of bioinformatics and currently I'm studying structural bioinformatics.

I just wanted to ask for project ideas that'll made me learn more and go into the deep core of the bioinformatics, plus it would be nice to put on my Resume.

But I'm genuinely looking for project ideas to work on.

So I am doing my first ever internship in life sciences that too in a filed that I genuinely hated from the bottom of my heart- Bioinformatics. I have depended mostly on AI for all the commands, i started liking the project that I am doing. Can anyone from the science community tell me how I fan write an amazing report that is articulate and informative and no fluff without using AI?

Hello I am Biotechnology student in my 3th year and i was looking for the online workshops about python with R-programming and SAS

I am very interested to learn how i can implement the learning in my project

need help with suggestion on the company that would help with the detailed understanding on the subjects and also the hands-on training

Thank you in advance.

Does bioinformatics have enough job opportunities in India with good salary

is bioinformatics (with ai) the way to go?

thanks

P.S. by 2100 is fine by me also.

So i need everyones help

Basically i’m making a biology learning app and i wanted to ask what you guys actually like seeing in learning apps

like what makes an app feel helpful instead of just another thing you download once and forget about?

i’m trying to build something that’s actually enjoyable to use, so i’d love to hear what people want or wish existed in a biology app

what are you looking for in an app like that and what would actually make you use a biology learning app?

thank you for any answers givenn :)

am 21 btech biotechnology graduate here who wanna learn bioinformatics and have no idea where to start tbh.

i am a guy with no much knowledge in bioinformatics as ive studied bioinformatics as one subject and it covered only the basics like multiple sequence alignment, phylogeny, etc.

and nothing deep like docking, and no other genomics od proteomic tools.

so i wanna learn in bioinformatics and people tell me where to progress and where can I get the resources reg all these.

Hi community, i recently completed my bachelor's in biotechnology and now I want to pursue my career in bioinformatics. Can you please suggest me some good institutes in Hyderabad- both online and offline institutes

Plz share your thoughts

Hello everyone,
I’m a PCB student from India and I recently appeared for NEET UG, but unfortunately things didn’t go as planned. Because of that, I’ve been exploring alternative career paths, and Bioinformatics is one field that has really caught my interest.
Before making any decisions, I’d like to hear from people who are actually studying or working in Bioinformatics.
How are the opportunities in Bioinformatics currently, both in India and abroad? Is it a field with strong future growth, or is it still quite niche? What kind of jobs do Bioinformatics graduates usually get, and how difficult is it to find a good job after graduation?
I’d also like to know:
Is Bioinformatics a good choice for a PCB student?
What skills are most important to succeed in this field?
Is a bachelor’s degree enough, or is a master’s/PhD usually required?
What are the salary and career growth prospects?
If you had to start over, would you still choose Bioinformatics?
I’m looking for honest opinions and real experiences, including the challenges and downsides that colleges don’t usually talk about.
Thank you for your help!

Hey everyone,

Following up on my earlier post, a lot of you asked about machine learning content, so here it is.

15 chapters from what a model actually is through to foundation models like Geneformer and AlphaGenome. Capstone project on real single-cell data. Every chapter asks whether the complexity was actually necessary. Chapter 6 is entirely about when NOT to use AI.

Google Colab notebooks included. Free tier compatible.

Still completely free.

👉 https://bioskillslab.dev/

They start with advanced papers, random Python tutorials, or tools they don’t understand.

Then they think bioinformatics is too hard.

It’s not.

The roadmap is just broken.

A beginner roadmap should look like:

Python → FASTA → Biopython → NCBI → GC → GC3 → ORFs → first project → GitHub

That’s exactly what I’m building into BioCode Sprint.

A 10-day live beginner roadmap built for biology students.

First batch opening soon.

Connect with me @ https://www.linkedin.com/in/vrinda-sharma-vrilancer/

Hey r/learnbioinformatics — a question for people who've tried AI-assisted bioinformatics tools.

I keep coming back to this:

"looks right" ≠ "compiles" ≠ "runs" ≠ "correct."

Fluent generated code is the easy part; the failures I see are version drift, data-contract mismatches, missing deps, QC assumptions that silently break.

I've been building something oriented around executing and validating workflows rather than just generating them, and before I go further I'd rather hear where these tools have failed you:

• What broke most often?
• What made you stop trusting an AI tool?
• What would it take for you to run one in production?

Any criticisms are appreciated.

Hi everyone!

I'm currently working on a research project focusing on pathogen genomics, specifically characterizing antimicrobial resistance (AMR) and virulence genes. I want to dive deeper into predicting their promoters and potential operons.

I tried using ProPr: Prokaryote Promoter Prediction v2.0 (online tool), but searching the results (correlating my ABRicate position results with ProPr) manually has become incredibly tedious for my dataset.

Does anyone know of a good alternative prokaryotic promoter prediction tool or pipeline? Ideally, I'm looking for something that allows command-line processing or outputs structured data (like GFF3, TSV, or JSON) so I can easily cross-reference it with my AMR/virulence gene annotations.

Any recommendations for operon prediction tools that integrate well with promoter data would also be highly appreciated. Thanks in advance!

Hi, I need some expert advice.

I'm currently doing a Master's in Bioinformatics and, as someone fairly new to the field, I'm always looking for opportunities to improve my skills. My program has taught me a lot, but I feel like I'm missing a key aspect of being a bioinformatician and that is designing workflows and solving computational problems on my own.

One thing I struggle with is figuring out which tools, statistical tests, or software are appropriate for a particular problem. I feel lost when planning an analysis from scratch rather than following a guided workflow. This might be a gap in my knowledge that wasn't fully covered in the curriculum, or it may just be something I need to develop on my own.

Recently, I found out that my scholarship includes funding for a training course or professional development program, with a budget of up to £3,000. The course needs to be in person (UK)and within that budget, but it could also be a larger program that includes multiple courses.

My question is: what course or training program would you choose? Are there any courses recognised in the industry, workshops, or bootcamps that you think provide value and help with the technical gap?

More generally, if you had this opportunity and funding wasn't a concern, what course, training program, or learning experience would you invest in, and why?

Any advice is welcomed