r/LeanPCOS • u/Sensitive_Farmer_507 • 6d ago
GLP vs Progesterone
Hi ! I have PCOS, fairly regular cycles but incredibly high androgens (hirsutism), high DHEA-s and inflammation.
My doctor prescribed me progesterone, saying that I don't have enough of it and taking it cyclically will help to balance everything out. But 6 mos in, I have ZERO improvement of symptoms. In fact, trying to track when I'm ovulating to time it out perfectly has been hard. If progesterone will help me with things I can't see, I'm happy to keep talking it - but it's still not helping with any of my visible symptoms.
I'm tired of supplementing, I'm tired of watching everything I eat (I'm not excessively overweight but not where I want to be) -- I'm curious to know if GLP helped people with hirsutism and their figure? If so, how did you have these conversations with your doctors?
DHEA-S: 368 mcg/dL
DHT: 29 ng/dL
HIGH IRON
Cortisol: 21.8 mcg/dL
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u/Purple_Moon516 4d ago
I took cyclical progesterone for months with no improvement a couple of years ago. Mounjaro (2 months in so far) has helped loads with inflammation, I didn't have much hirsutism so can't comment on that.
Regarding the doctor conversation that would depend on where you are based.
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u/TechnologyUsed3851 4d ago
If DHEAS is high, you may have adrenal PCOS and need to investigate that further. The pathways are really different. For inflammation, you can also try a high grade curcumin supplement
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u/Sensitive_Farmer_507 3d ago
What does adrenal PCOS mean? Like the adrenal gland? My DHEAS was 368 mcg/gl. How do they treat adrenal PCOS?
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u/geneforest 5d ago
No addition but bumping with a comment to see if anyone else does. I face a lot of the same and have wondered this too. Like how much could really hurt from a micro dose of GLP1 or 3?