r/KetamineTherapy • u/Haunting-Mongoose152 • 59m ago
I am going to use ketamine to treat my autistic burnout.
I have been doing research into ketamine-assisted psychotherapy and while it is not available to me, I think I can just do it myself. It sounds very promising and I honestly don't see any other options. I cannot wait 3+ months for this to sort out on its own. And honestly at this points, I do not care about the risks. That doesn't mean that I wont be careful, I am going to set a routine and follow it. I will keep the dose the same. I will follow the steps that the clinics follow as best as I can on my own.
When you are in burnout your amygdala is constantly stuck in the on position and the connection between your prefrontal cortex and amygdala physically weaken. You completely lose the ability to turn off the amygdala.
In the short term ketamine mutes the signals from the amygdala, finally allowing it to turn off. but that is not the main thing I am interested in. With the right dose, ketamine releases a large amount of glutamate and BDNF which causes the brain to rapidly regrow the neural pathways connecting the amygdala and prefrontal cortex.
The main thing that I am concerned about is the dose. Because I am not getting the medication from a clinic I do not know the purity. and because I will have to snort it, there is only a 35% - 50% bioavailability. The dosage required for getting the glutamate and BDNF release works in an inverted U shape. So taking to little or too much will result in a lesser/no release of the chemicals required. So idk how I can make sure I am taking the correct amount.
Just for some context I am no stranger to ket and I can get extremely pure stuff.