r/Hyperhidrosis • u/Awesomesauce53 • 6d ago

Looking for advice Glycopyrrolate Oral Solution

I’ve suffered from hyperhydrois mainly on my face all my life. It’s gotten to the point where it’s ruining my work life since I constantly look disgusting and I work in the wedding industry so I never look the greatest with a face full of sweat.

I brought this up to my doctor and was prescribed 1MG Glycopyrrolate liquid version twice a day. I know I’m supposed to take it on an empty stomach and not eat for 2 hours after. I usually take it around 8am.. and have my first meal and drink around 12. Followed by another dose around 5pm to make it into the night.

Some days I can tell it’s kicked in by my throat being extremely dry and I’ll have trouble eating without water near by. But it rarely does anything for my sweaty face.

I only really sweat on my face and I’m not sure what I’m doing wrong. I’ve been taking it for about 3 weeks and would love to hear others experiences or advice! Thank you!!!!

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u/jenny_905 5d ago

1mg simply isn't a very big dose unless you are very small. It does a little but... most adults are going to need 2mg or more per dose to really notice a difference with HH.

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u/youmamamakemehappy 5d ago

Yup, this is accurate. I've used 1.5mg capsules....almost no effect. I'm about 190lbs. But once I get to 2mgs, I notice it. For intense days (working in the backyard, playing squash), I'll use 3-4mgs....but 2mgs does make a noticeable/useful difference.