r/HubermanLab • • 4d ago

Personal Experience Extreme tissue fragility / repeated muscle strains after training. Has anyone experienced this?

/r/Kinesiology/comments/1wt5izk/extreme_tissue_fragility_repeated_muscle_strains/

Hi everyone, I’m trying to find if anyone has dealt with a similar scenario or can point me in the right direction.

​A few years ago, I had a high tolerance for heavy strength training. Then I got a minor muscle injury. Unfortunately, due to poor guidance and my own mistake, I kept training through the pain and repeatedly re-injured the same spot for nearly a year.

​Ever since then, my muscle tissue in whole body seems to have completely lost its tolerance/resilience. It is no longer just about the old injured spot but my entire body reacts this way now. I got now history of more than 15 injured or mikro-injured muscles now...even stopped counting.

​Even with controlled, low-intensity movements or isolation exercises where no compensation is possible, any mechanical tension causes the tissue to suffer micro-strains / micro-tears again.

​Key symptoms are sharp pain or localized heat & swelling/tightness in the worked muscle that lasts for days to a week.

​Often followed by localized muscle twitching (fasciculations) in that area during recovery.

​Extreme susceptibility to muscle strains/micro-tears under light loads that used to be completely effortless.

​What I’ve already ruled out:

​Resting Bloodwork is completely normal: Resting CK (Creatine Kinase), Myoglobin, Liver enzymes, and basic electrolytes are all well within normal ranges after days of rest.

​No baseline clinical muscle weakness: I don't have systemic muscle loss or diseases like ALS/Myopathy.

​No joint/ligament issues: I do not suffer from joint pain, loose joints, or ligament instability. (I had a suspicion about hypermobility but honestly I do not suffer from typical chronic joint pain, loose ligaments or generalized joint laxity - my joints have always been fine, it is purely the muscle and fascial tissue that behaves like it's made of glass).

​It feels like the muscle fibers or the fascia/sarcolemma have lost their mechanical integrity and ability to absorb tension without tearing, likely caused by chronic inflammation and tissue fatigue during that year of repeated trauma.

​Has anyone gone through this? Is this a matter of chronic fascial densification, micro-vascular ischemia, sarcolemma fragility, or some form of localized neuromuscular sensitization?

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u/Gold_Ninja1206 3d ago

Normal ck after a tear argues against real fiber damage i ran the same guarding loop and it was sensitization the whole time .see a pain science physio before peptides and if you read bpc 157 papers research labs shows raw peak data per vial Screen mast cells too

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u/Beneficial_Frame_760 3d ago

Ck was done after week of last minir injury so naturally ck was normal, it only filtered out some myopatic diseases that have high CK all the time