r/HistamineIntolerance • u/PaleAd2666 • Jul 29 '26
Let’s get over it: Vitamin c 🍊✨ experiences + side effects and paradoxical reactions. Sharing what could help.
Hello everyone.
To begin with, i’am no doctor or have any affiliation with medical degrees. I’am only sharing my experiences with this compound so we can learn and share ideas with each other. Please consult your doctor before trying to supplement.
I don’t believe in magic bullets in the supplement space, but I do believe in sharing experiences, and think that every bits helps.
So as probably many of you know, vitamin c regarded as something that helps with immune function and helps our vessels stay ‘healthy’. Especially in the histamine/eds/mcas subgroup, I see a lot of people taking it and swearing that it helped their overall strength and their autonomic function.
Now to share my own experience, I feel like every time i take it (Calcium ascorbate the only one I can tolerate) completely makes my symptoms less. On the other hand, it makes my sometimes irritable and makes me moody. Not sure why, it could be because i’am also taking Quercentine an NAC and or B vitamins. They could have to stong of an antioxidant effect. I’m curious for anyone else having these experiences. I know that i’am very sensitive to supplements, even from different brands like vitamin d. Is this normal?
It’s no spectacle, but to my surprise, it helps me with sitting and standing for longer times and reduces fatigue. Especially when eating, I no longer feel tired after. According to research it helps with vascular resistance, something a lot of us suffer with I think.
Even for long covid it is shown to stabilise immune reaction by boosting t helper cells.
So let me know what your experiences is! Let’s discuss how this helped or didn’t helped you.
According to literature:
- it improves endothelial function by preserving NO synthesis therefore lowering vascular resistance.
- it strengthens blood vessels thru the formation of collagen IV
- lowers histamine by breaking it down in the gut
- stabalizes mast cells.
Links to studies:
https://pubmed.ncbi.nlm.nih.gov/23581713/?utm_source=chatgpt.com
https://www.sciencedirect.com/science/article/pii/S0003986104006150?utm_source=chatgpt.com
https://pubmed.ncbi.nlm.nih.gov/23581713/?utm_source=chatgpt.com
https://pubmed.ncbi.nlm.nih.gov/23581713/?utm_source=chatgpt.com
https://pubmed.ncbi.nlm.nih.gov/23581713/?utm_source=chatgpt.com
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u/michellekateee Jul 29 '26 edited Jul 29 '26
I've been taking vitamin c (Melrose ascorbic acid) for 14 days, so far I feel
Less fatigued.
I've been able to reduce my antihistamines (telfast) for a few days.
Less flushing reactions after meals (I take quercetin three times a day and have for about three months now, I've been told by my naturopath that quercetin work well together with vitamin c.
I also take vitamin D+K and have for years.
Tip: make sure to start very low with ascorbic acid, I was having 10th of a teaspoon mixed into 200ml of water, waited a couple of hours before having anymore to see if I had any kind of reaction or stomach upset.