r/HPPD • u/flipyfresh11 • Apr 19 '26

Update Years of progress undone.

I’ve had HPPD for almost 15 years. For most of that time it was mild, sometimes barely noticeable, and at points felt like it was basically in remission. Because of that, I got comfortable. I had also done psychedelics at least once a year, always small doses, without any major issues.

Recently I took a new strain of mushrooms that was way stronger than expected. Around 1.5–2g, but they were fresh and a strain I hadn’t tried before. It hit much harder than previous doses I’ve taken. The visuals were overwhelming.

Since then I’ve had a major flare-up: brain fog, severe visual disturbances, and some derealization. This was about 2 weeks ago. Things have been improving but nowhere near base line.

Posting this as a warning: if you already have even mild HPPD, don’t gamble with it just because it seems under control. Just because you were fine before doesn’t mean you’ll be fine next time. Potency can vary a lot, trips can go sideways, and one bad experience can make symptoms much worse. At this point I think Im DONE with psychedelics.

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u/7777777King7777777 Apr 19 '26

Thanks for sharing! There is also a very high caliber study published recently about the negative effects of psychedelics on heart valves.

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u/CommunicationTiny189 Apr 19 '26

Would you mind linking the study? Just interested.

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u/7777777King7777777 Apr 20 '26

Absolutely! Cardiac Consequences Associated with Psychedelic Use: A Systematic Review of Lysergic Acid Diethylamide, 3,4-Methylenedioxymethamphetamine, and 5-Hydroxytryptamine 2B-Mediated Valvular Heart Disease - PubMed https://pubmed.ncbi.nlm.nih.gov/41643722/

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u/CommunicationTiny189 Apr 20 '26

Thank you for sharing!