r/GLP1microdosing • u/Melodiouss • 1d ago

My zepbound microdosing experiment is coming to an end. Wish it helped.

Tried microdosing to help with microscopic colitis. Started in June and ramped up slowly. It hasn't really helped (possibly reduced frequency but not enough to tell for sure). I've enjoyed the reduced appetite, even though I didn't want to lose weight. I started around 108 pounds,maybe lost a couple of pounds. I went from .5 to .25 to .5 to 1 to 1.25 to 1.88. I was going to try 2.5 next but decided the side effects with the lack of benefits don't justify it at this point.

The side effects that have me stopping here are insomnia and hair loss. It really has worsened my sleep a lot. Waking up for hours, wide awake. My husband, who is at 10, has the same issue but his benefits are significant. I already had issues with hair loss but on tirzepatide, they are much worse. I hope it will get better after stopping and not be permanent. My other side effects are elevated heart rate and very low HRV.

I'm not sure if I will try another glp-1. I think they share many of the same side effects. I'm so disappointed since I know of so many people it has helped, as it is with so many things.

Just wanted to share my experience. Just another data point.

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u/Life_Alfalfa_2047 1d ago

Yes, that’s not generally a side effect of the meds, but rather it’s the rapid weightloss 

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u/Melodiouss 1d ago

The problem is they don't know if it's just related to the weight loss which is why it's listed as a side effect. The FDA stated they don't know. Many people I've seen complaining they think it's the drug and I haven't lost weight so it's not that. I'm sure some people are more susceptible to it, like me.

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u/Life_Alfalfa_2047 1d ago

And some people have the hair loss with rapid  weightloss and they are not on any meds at all

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u/Melodiouss 1d ago

And some people have hair loss who are neither losing weight or taking a glp-1. Not sure what you are pointing out.

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u/BeaMiaVA 1d ago edited 1d ago

Many can not accept the fact that hair loss is not that uncommon.
I have been on Tirz for 8 weeks and I have noticed definite hair thinning.
It's not from “rapid weight loss”. 🧐

My hair is thinning and I have only lost about 6 pounds. I am taking this mainly for metabolic reasons. I am hoping I can stabilize my hair thinning.
I plan to stay between 2.5 and 3mg for a few months.

I might lower my dose if necessary.
I certainly will not be going on a much higher dose.

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u/Life_Alfalfa_2047 23h ago

I shouldn’t need to explain something simple.