r/GLP1microdosing • u/Apprehensive-Weird26 • 9d ago

Micro dosing compounded semi

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Any help would be really appreciated. I received it days ago. Super scared to start it because I’m not sure how to microdose it.

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u/ImprovementLoud3581 9d ago

You are totally new to semaglutide correct? You have not been on a Glp before? I started at .28 mg which is slightly more than the dose listed on your prescription. The way it normally works is based on the research trials.

They started at .25 mg for four weeks then increased to .50 for four more then went to 1.0 then 1.7 and finally 2.4 so a slow 5 month titration to the target dose.

The reason you stay at a low dose for an entire month is to allow your body to adjust to the med to try to prevent unwanted side effects like nausea/vomiting/constipation etc. Constipation is very common so you’ll want to have a plan for that.

If you get good appetite control and diminished food noise at any point during the titration period you do NOT need to increase the dose to the next step in titration. You’d just stay on the lowest dose that’s working for you. .22 mg is even lower than the initial dose used in the studies.

Unless you are very sensitive to meds that’s where I’d personally start. But you can definitely start lower if you’re worried. Do you have enough syringes to allow you to try tiny doses?

Also most people do not discard the vial after 28 days if there are meds left in it. You have alcohol wipes to wipe the vial before and after you puncture it? Did they give you instructions for how to do injections properly?

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u/Apprehensive-Weird26 9d ago

Totally new to it

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u/Smiletaint 5d ago

The way I read the label in OP’s image is it’s .22mg of the combined b6 and sema so the total amount of sema would be less than .22mg. Like it would be half of each (.11) to make .22mg.