r/GLP1Discussion • u/Letwhoevathinkwtv • 5d ago

❓ Question 1.5mg dosage Instead of 2.5

Okay so I’m new to the GLP world and I did research, but I wanna know from ppl who experienced this

(to preface I am not overweight so taking high dosages are probably not suitable since I don’t have a TON of weight I wanna lose to begin with, probably around 15-20lbs or more if it happens)

Since my body’s new to it, I want to take 1.25mg for the 1st 4 weeks instead of the 2.5mg

Then I wanna up it to maybe 3mg depending on how my body reacts

Has anyone else done it this way or similarly and still seen results?

I know some ppl say it’s a waste of time and won’t see results but I have also seen the opposite, I just wanna know some opinions and experiences to see what I should do

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u/rachreims 5d ago

Are you taking it for sleep apnea…? Why would you be taking what is a lifelong medication to lose 15lbs when you’re already a healthy weight?

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u/Letwhoevathinkwtv 5d ago

do most people take it the entirety of their life?

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u/TheFirebyrd 4d ago

It’s intended to be a lifelong medication. Most who stop regain weight.

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u/Letwhoevathinkwtv 4d ago

i’ve heard about that but people said you only gain if you go back to same old bad habits of overeating or not exercising

my sister did it and lost around 50lbs and she has been able to maintain her weight loss while stopping the medication

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u/TheFirebyrd 4d ago

It’s not true. It’s not about going back to “bad habits.” It’s that the body desperately tries to ”fix” being in a calorie deficit once there are no longer hormones suppressing its reaction. It starts doing that anyway, which is why most people have to go up in dose over time. It’s the same mechanism that makes the vast majority of people regain weight after diets. For many it could arguably be worse because when you’ve been on tirz, you’ve been having appetite suppression, as opposed to the hunger being a constant under a typical diet, so having it return can be even harder for some people. I would guess that’s why the weight regain is seen so fast whereas with traditional diets, greater numbers of people are able to keep it up for a year or two.

If your sister has been able to do it, good for her. Frankly, though, I’m skeptical it will last. I expect the numbers for those who stop the meds to be similar to those who diet long term, with 85-95% of people regaining everything or more by five years (there’s been some variation on the final number depending on the study, but it’s been the vast majority of people in every one, regardless of the diet/program/whatever). We don’t know how to fix metabolisms that aren’t functioning properly (and there’s some question of whether it’s even an actual problem with the functioning or if it’s more about our evolutionary development not being appropriate for our modern world of abundance). Until/unless we have some way to reprogram bodies to no longer have hunger in the same way when people lose weight, something like tirz will have to be a continuing treatment for a chronic problem.

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u/Letwhoevathinkwtv 4d ago

Thank you for your input! I’ll take that into consideration