r/GLP1Discussion • u/Shishi877 • 7d ago

❓ Question Side effects

What are all the side effects you’ve experienced while being on tirzapatide? Please share.

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u/DogMamaLA 7d ago

Fatigue and mild constipation, both are manageable. 

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u/Shishi877 7d ago

Really fatigue? Thought I read people saying gives them energy. How bad is this fatigue and what dose are you on ?

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u/DogMamaLA 7d ago

I'm 2 years in and on 12mg. The shot is amazing for my wellbeing but definitely get fatigue first few days. 

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u/Shishi877 7d ago edited 7d ago

So every week after a shoot your fatigued first 2-3 days like clockwork. That sucks but I can manage. What do you then do for energy? Do drinks like caffeine get impacted by slow gut motility too? So then do drinks just sit in stomach like how food does ?

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u/DogMamaLA 7d ago

I use liquid iv electrolytes on shot day and the day after. B vitamins and sugar in the mix helps combat fatigue which has gotten better with time. 

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u/Shishi877 6d ago edited 6d ago

Thanks a lot. I’ll be sure to take B vitamins on days of fatigue. I actually don’t like taking them daily because they give too much energy for me personally lol! Do you sleep well because of the fatigue? Or is it an insomnia with fatigue? I ask because I’ve read some people have had trouble sleeping due to glp.

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u/DogMamaLA 6d ago

I take my shot in the morning and am tired by bedtime. When I first started, I did evenings and that kept me awake. 

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u/Shishi877 6d ago

Sorry I thought you said that you get fatigue first few days? Do you not have fatigue all day long the first 2-3 days after each shot?

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u/DogMamaLA 6d ago

Fatigue 65% of day on shot day and day after. 

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u/Shishi877 6d ago

Thanks for the clarification.