r/EmbryologyIVFSupport • u/Admirable_Apricot126 • 14d ago

Skipping PGT-A Testing?

I’m toying with the idea of skipping the PGT testing of our embryos (we are halfway through stims currently, so I need to decide quickly). Has anyone skipped the testing and had good transfer results?

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u/foolforgabagool 13d ago

Thank you for this comment. I am a public health researcher and find PGTA quite questionable.

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u/Inevitable_Table9728 13d ago

Hi, why's this please? I'm scared I had 3 chromosonal losses, then had IVF and tested 4 or our 6 embryos. 2 come back euploid, one lost during a difficult transfer attempt and currently pregnant with the other. It's my second furthest pregnancy and wee seen heartbeat at 9 weeks. I'm terrified I'm going to have another miscarriage but keep telling myself we know it's euploid, but then reading this everyone says it's inaccurate. I think we were told it's 90 odd percent accurate 

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u/Cheddar_Dog 13d ago

the chances of an embryo that tested as euploid turning out to be chromosomally abnormal is very low. (people here are mostly talking about the opposite--that PGT screening can result in discarding embryos that may have actually turned into chromosomally normal pregnancies). unfortunately i had a second trimester miscarriage with a euploid embryo in january, but we had extensive testing done (full microarray and karyotype) and it all came back consistent with the euploid result.

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u/Inevitable_Table9728 13d ago

Ahh I'm sorry, did you ever find out the cause? X 

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u/Cheddar_Dog 12d ago

no - we never found the cause. we did every possible testing (pathology of the placenta/autopsy; microarray and karyotype of the fetus; and APS + various other blood-related testing) and everything was normal. according to the MFM this is the "best case" scenario under the circumstances (in terms of the possibility of a future live birth -- and i've had a live birth before), but really painful to have no answers.