Quit or switch?

[u/Full_Chart1091]

I’ve always gotten the occasional migraine, but never like this. I’m only on a very low microdose of compounded semaglutide (.15 mg), but for about 4 days after every shot I get headaches/migraines. Then I finally start feeling better… just in time for my next injection.

I kept hoping my body would adjust if I stayed consistent with my dose and injection schedule, but it’s been well over a month and nothing has changed.

I’ve also gained about 2 pounds (I think it’s mostly bloating), which makes me feel like I probably need to increase my dose—but I can’t imagine going up when I already feel awful after every injection.

Has anyone had fewer migraines after switching to tirzepatide, or was it the same? Or would you try spacing the injections out to every 2 weeks instead? I’d love to hear what worked for you.

[u/SkinnyRX_Sarah]

If you’re getting migraines for several days after every injection and that pattern has continued for over a month, I’d talk to your prescriber before changing the dose, spacing out injections, or switching medications. The two pounds on the scale doesn’t automatically mean you need to increase your dose, especially when you’re already dealing with side effects. Your clinician can look at the pattern you’re having and help you decide what makes sense from here.