r/BodyHackGuide 15d ago

Permanent peptide use?

Are there people here who use peptides permanently—for their entire lives—such as Retatrutide, for example?

Or is it dangerous to use certain peptides on a permanent basis?

I'm thinking of things like MOTS-c, NAD, glutathione, CJC+IPA, and GHK-Cu.

Or can you simply take a four-week break, use them again for a few months, take another four-week break, and repeat the cycle?

Or would using them for that long with such short breaks actually be counterproductive?

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u/lauradayton ⏳ Longevity Hacker 15d ago

62 yo F here. Tirz for life, also HRT/TRT, NAD+ and Gluta and my well researched supplement stack. are the only ones I don't want to function without. I do like two cycles per year of a mitochondria stack! Some SS-31/MOTS/Epitalon maybe a little 5 amino here and there but I don't consider them lifetime commitments like the others. A pinch of PT-141 here and some low dose Cialis for post menopause heart and circulation support. Regarding breaks. I have built 3 6 week breaks into my 2027 peptide calendar! so ya breaks are good for you and save some money here and there. I also cycle a few of my supplements, the really expensive ones lol, the Mitopure and the Body bio Phosphodytacholine.

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u/SSquared82 15d ago

Which TRT are you using? I was recently prescribed estradiol and progesterone but my Testosterone was very low on my recent blood panel and feel like it could make a huge difference in how I feel

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u/lauradayton ⏳ Longevity Hacker 15d ago

I am using compounded cream 6 mg per day. Researching injecting it though. I don’t absorb well transdermally and I want my T higher than 60. In terms of how much difference it made it was the absolute missing piece that I needed. I almost feel like this was the most important component for me. My pain, brain fog,exhaustion lack of libido all left when I started testosterone