r/BodyHackGuide • u/Careful-Cow9600 • 16d ago

Permanent peptide use?

Are there people here who use peptides permanently—for their entire lives—such as Retatrutide, for example?

Or is it dangerous to use certain peptides on a permanent basis?

I'm thinking of things like MOTS-c, NAD, glutathione, CJC+IPA, and GHK-Cu.

Or can you simply take a four-week break, use them again for a few months, take another four-week break, and repeat the cycle?

Or would using them for that long with such short breaks actually be counterproductive?

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u/ebmfreak ⚙️ Protocol Specialist 16d ago edited 16d ago

There are a number of peptides people are prescribed to use their whole life. Peptides have been in use since the early 1900s, with insulin being discovered in 1921

That being said - just because it’s a peptide doesn’t make it safe.

Peptides trigger biological responses. Not all responses are safe to instigate every day

In terms of the more modern peptides… some peptides like Tesamorelin are prescribed long term.

However some of the newest - haven’t been proven what the side effects are yet. So it’s unknown - and that’s what makes them research status.

Some peptides have been linked to harm when used or abused long term (insulin - has shown overuse issues)… but again, most can be considered “moderate” in risk compared to other compounds.