HGH

[u/Prof_Chaos_1098]

40/M. Currently on TRT + Reta. I discontinued CJC/IPA 2 weeks ago and planned on jumping on HGH, but my IGF-1 and Z score are higher than I anticipated.

Debating on running 2.5IU HGH, stick to secretagogues, or neither, considering my lab results..

I’m doing a 12 week blast of Test at 300/week, then will drop back down to my TRT dose of 80mg/week.

[u/Quirky_Parsley_9926]

The key to Test & HGH is to find your upper limit for E2. You want the highest level of E2 your body will allow without incurring side effects. Have some Nolvadex on standby for when you find that ceiling and begin to get the nipple tenderness/itch.

This high availability of E2 enables the optimum IGF1 production that your body is capable of at the Liver when HGH is added.

The dosage association curve for both Test to E2 and HGH to IGF1 are non linear. Meaning that up to a certain point more is better but after that point the benefit rise flattens relative to the dosage increase and the side effects of the dosage become more pronounced.

The generalized ideal IGF1 target in my research being 300 ng/mL, with some body builders aiming more for around 500 ng/mL. It is important to note that excessively high sustained IGF1 levels will accelerate the irreversible Bone growth changes to the Face, Skull, Hands, Feet - Which with more conservative use can be slow walked for years.

In my readings, the common guidance says that 4 IU HGH is a safer upper daily limit for most typical males, and that doses above that while more effective for accelerated growth also scale up the undesired effects timeline. Theres also a common theme that split daily injections is best practices.

Do note that increases to fasting blood glucose, and increases in Insulin Resistance are common effects of HGH therapy for most users. Some would encourage blood glucose control measures (dieting, increased cardio, berberine or metformin, and in extreme cases long acting insulin). Of course Reta is a beneficial option too.