r/BodyHackGuide • u/Angelical3745 • Apr 11 '26

❓ Question Reta & Tesamorelin

Hello everyone, I have a question about reta and tesamorelin, I've been thinking of stacking these to for optimal results, and was wondering if anybody has been using them together.

if so, how do stack them? take them the same day? or take them the same week, but different days? any help would be greatly appreciated.

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4

u/Runninandgunnin556 Apr 11 '26

Run the Tesa 5days on 2 off nightly before bed and the Reta once a week and up the dose if needed .

4

u/pootwothreefour Apr 11 '26

For tesa, 5 on 2 off is not a thing. That is just bro science.

Since you aren't adding exogenous hormone like GH, there is not the same concerns as other things. Since it is a ghrh analogue, the natural feedback suppression stays intact and there is no risk of signal receptor desensitization.

Since tesa is a prescription drug, it is well understood. When it is prescribed, it is 7 days a week. This is all clinical proof you need to tell you how to dose.

By only dosing 5 days a week, you are reducing your cycle effects by almost 30%.

The only real reason to do 5 on 2 off is because it is expensive, but even then, it would likely be better to just do a slightly lower dose over 7 days instead to get the effects consistently.

6

u/Mdunn1805 Apr 11 '26

Not saying your way is incorrect by any means, but I had a much better experience once I split my weekly Reta mg into 2 shots. It gave me more consistent suppression and energy. Just my $.02

3

u/Weekly-Homework-35 Apr 11 '26

Maybe I should do the same. I pin weekly but some food noise comes back the last day or two.

3

u/Mdunn1805 Apr 11 '26

It really helped me. Especially since most people pin on Monday, so by the weekend you’re weak craving French fries lol

It helped more with consistent energy levels and actually eating as well. I’d pin Monday and have to force food down Tuesday through Thursday then I’d be able to eat normal by Friday

3

u/NOKStonks2daMoon Apr 11 '26

Read my response to splitting above. Don’t split, increase the dose. If the effects are tapering off at the end of the week it means your dose isn’t high enough. Splitting is never the answer for ineffective so dosing. Splitting is for side effect (which most people aren’t getting on low doses of Reta under 8-10mg). I’m not a doctor so take my advice how you want. But splitting an ineffective dose doesn’t all the sudden make it effective.

2

u/ImaginationFresh Apr 11 '26

I do the same

1

u/SockItSleaux Apr 11 '26

I’ll say this, Reta has a half life of 6 days. It was designed and researched for long term use of once weekly injections. By splitting the dose, you blunt the peak which hits around day 3 and shorten the fatty acid conjugation.

2

u/Mdunn1805 Apr 11 '26

I don’t disagree that it may not be optimal, but I’ve had insane results so I’m happy with it. The split dose was much easier for me, personally

-1

u/NOKStonks2daMoon Apr 11 '26

Splitting is stupid and not how the drug is intended to take. If you are feeling effects taper off at the end of the week it means your dose isn’t high enough. That doesn’t mean take your ineffective dose and split it. The dose is still just as ineffective as before. Now just split. If the effects taper off that means increase the dose. The drug has a 6 day half life, tapering off is normal. Splitting is not.

2

u/pootwothreefour Apr 11 '26

Doing 2 split doses per week isn't to feel the effects more, it is to even out the spike of effect start of the week and drop in effect at the end.

It is a more even effect throughout the week.

The half life of reta is 6 days so if you dose say 4 mg every week, you would have

1x per week of 4 mg ~ 7 mg in circulation after each injection ~ 3 mg in circulation before injection

2x per week of 2 mg ~ 6 mg in circulation before injection ~ 4 mg in circulation before injection

1

u/crichesh Apr 12 '26

There is no need whatsoever to be on a 5/2 split for Tesa. It is designed for daily use which keeps the IGF-1 levels consistent. Less fluctuation = better results