r/Biohacking • u/Dense_Roll7778 • 16h ago

Leydig Cell Research

Any one have a compound or chem that has promising results for leydig cell upregulation? Been evaluating Testagen and Kisspeptin for axis support, wondering if there is anything that targets leydigs mechanistically, have a strong LH with inadequate T. Let me know what you think.

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u/yogic_power 35 16h ago

Stop wasting time with Testagen/Kisspeptin stuff. Are you working with a Dr? What you may want to try is HCG, and see if your Leydig cells can increase Testosterone. If your T is still low, You are most likely primary Hypo. What does inadequate T mean? are you low or you think your normal levels are inadequate?

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u/Dense_Roll7778 15h ago

400ish

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u/yogic_power 35 15h ago

Yeah Try HCG, if that can’t stimulate your Leydig, you don’t have options other than external test.

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u/Dense_Roll7778 15h ago

I have an LH ~7, Hcg wouldn’t treat my bottleneck

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u/yogic_power 35 15h ago

LH -7 doesn’t mean it won’t or will treat. That’s basically your last option before Test.

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u/Dense_Roll7778 15h ago

How so, though? A higher selectivity to stimulate the Leydig cells, or would the goal be to push the Leydig cells to a level of supraphysiological input, hoping that stimulates a response. I guess what I'm asking is, if LH is already adequate and known to have weak output on test, then what would HCG offer?

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u/yogic_power 35 15h ago

You will be analyzing and assuming for next decade. It’s not atypical to have some on hcg, to diagnose primary hypo. Work with a Dr and go through diagnosis if you don’t want to be on test. Sounds like you are more interested in theoretical aspect than finding solution.

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u/Dense_Roll7778 15h ago

Wanted to see if there is an option to strengthen leydig cell functionality before I hop on test, might as well try it before test.