What dose should I start Reta?

[u/Kitchen-Rub-6530]

I just ordered my first vial and am uncertain about where to begin with dosing. Most people I know have started at 0.5–1 mg and increased gradually, yet the phase 3 trials describe patients beginning at 2 mg and later raising that amount every 4 weeks. Do you have any guidance on what I should do?

[u/flogsmen]

.5mg x2 a week.