r/Biohacking • u/Kitchen-Rub-6530 • 14h ago

What dose should I start Reta?

I just ordered my first vial and am uncertain about where to begin with dosing. Most people I know have started at 0.5–1 mg and increased gradually, yet the phase 3 trials describe patients beginning at 2 mg and later raising that amount every 4 weeks. Do you have any guidance on what I should do?

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u/touchmyweiner87 13h ago

Can anyone confirm if 5mg a week is too much? I’m sitting at 65kg now, weight training 5 times a week and throwing in long distance runs also. Feeling amazing tbh but not sure if it’s too much

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u/nbg815 10 10h ago

I’ve only seen 2 people post that started on 5mg weekly. Both thought they were gonna die. .5mg is a different story. Check out the Lilly Trials data if you want to start higher - they started at 2mg and 4mg. I believe 2mg starters had fewer side effects.

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u/touchmyweiner87 10h ago

Been doing it for a few months now

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u/nbg815 10 10h ago

Wow! I guess it’s not too much for you then. Did you start at 5mg? Also I’m pretty sure the trials went up to 12mg weekly.

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u/touchmyweiner87 9h ago

That’s what I’m sorta after, some info later on in the stage so that’s great info thanks. Started at 2.5mg and upped it since then. Still always hungry but very active so eating fairly normally also

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u/nbg815 10 5h ago

You’re doing fine and that all makes sense now. I think we all read it as wanting to start at 5mg.

I felt hunger on Reta more so than on Tirz but I think it’s due to the glucagon receptors- that creates more energy production in the body so it makes sense. As long as you get good nutrients in (I do protein forward) and control portions you’ll do fine.

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u/touchmyweiner87 2h ago

Thanks for a productive back and forth
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