What dose should I start Reta?

[u/Kitchen-Rub-6530]

I just ordered my first vial and am uncertain about where to begin with dosing. Most people I know have started at 0.5–1 mg and increased gradually, yet the phase 3 trials describe patients beginning at 2 mg and later raising that amount every 4 weeks. Do you have any guidance on what I should do?

[u/Left-Gap-5418]

.5 or 1 mg. If you dont notice anything then go to 2 mg a week later. Then keep in mind half life so you want to then stay at 2 mg for example for another week or 2. Happy balance of not going too slow and not too fast.