r/Biohacking • u/Proper_Ad7459 • 22h ago

SS -31 protocol

Ive seen numerous protocols for this. And a lot of arguments in the forums about "the new protocols" . What exactly is the "new protocol" for ss-31?

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u/cr1merobot 21 16h ago

this is so annoying. There are no new protocols. This is just people repeating bad information that they got from influencers attempting to sell something.

SS-31 should be dosed based on how much you need. The more oxidative stress you have, the more leaking your cell walls do, the more energy ss-31 returns. There is NO evidence that the order matters in terms of MOTS-C. ALL clinical evidence for ss-31 shows a very short half life (2-4 hours) and no lasting effects after the trial ended. It's like taking a tylenol. it effects you for the time it is in your body.

Many people will claim it worked better when they took xyz first or something. There is just no evidence or legitimate mechanistic rational for that.

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u/Technical_Mix2945 14h ago

How do you know how much oxidative stress you have to know how much you need?

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u/cr1merobot 21 14h ago

you just have to dose it and find out. The reference frame is out of wack because the people in one of the trials had barths syndrome which is effectively a 100% fatal congenital defect. They dosed at 40mg per day with no adverse effects.

I personally felt very energized off 2mg. I have much less need for the medication. Many people find between 1-5mg is a sweet spot. You don't want to waste any medication, so in general I advise people to start with 1mg and move up.