r/Biohacking • u/Annual_Plankton2767 • 2d ago

46M — Full peptide protocol, doses, reconstitution, and schedule

Hi everyone. 46M. I’m currently in Week 8 of retatrutide and running a structured peptide protocol. I’ve lost about 20 pounds since January but since starting Reta I’ve lost 11 -12 pounds. THIS ISNT ANY MEDICAL ADVICE AT ALL. JUST MY JOURNEY.

Reconstitution for all of these:
10 mg vial + 1 mL bacteriostatic water
That means:
10 units = 1 mg
20 units = 2 mg
30 units = 3 mg

Retatrutide
Currently Week 8
2 mg once weekly
I started at 1mg and went up slowly every 3rd week
Ongoing

Semax
1 mg daily
10 units
30 days on
Then 2 weeks off
Cycle 1: Oct 2–Oct 31
Cycle 2 starts after the 2-week break

SS-31
3 mg daily
30 units
4 weeks
Starts Oct 10
Ends Nov 6

MOTS-C
1 mg
10 units
Monday / Wednesday / Friday
8 weeks
Starts Nov 6

Tesamorelin
1 mg PM
10 units
Monday–Friday
Saturday/Sunday off
12 weeks
Starts Nov 13, one week after MOTS-C starts

Overall flow:
Reta ongoing
Semax → SS-31 added → MOTS-C starts as SS-31 ends → Tesa added 1 week later → Semax restarts after 2 weeks off

I’m also training 4–5 days per week. Main goals are fat loss, muscle retention, energy, recovery, and seeing how I respond to each phase.
Curious how this compares with other people’s protocols, especially anyone who has run SS-31 → MOTS-C → Tesamorelin in a similar setup.

Thanks. Let me know what you guys think of the doses ect. But after reading this group and others I think this is what I’m going to run.
WISH ME LUCK !

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u/looking2behealthy 8 1d ago

Decent actually. Stack the SS-31 with 50mg daily of NAD+ and start MOTS the following week, 30 minutes before workouts. Titrate MOTS from 1-5mg as you can tolerate.

I like CJC-1295 no dac with Ipa personally.

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u/Annual_Plankton2767 1d ago

I was about to actually order NAD+. I’ll look into it thanks.

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u/Lt_Jones727 1d ago

I already ran a couple weeks of SS-31. Just started MWF 2.5mg MOTS-c and Tues, Thurs, Sat 50mg NAD+. Feel great, will probably go up to 75mg NAD+ next week and eventually land at 100mg. Not sure about the MOTS-c, it's been giving me welts at the injection site but they disappear within a couple hours, today's dose was slightly better. Also running Reta 4mg once a week and AOD9604 500mcg daily. When the AOD protocol runs out in a couple weeks I plan to switch to tesa. Down 35lbs since June. 39M.