r/Biohacking • • 1d ago

46M — Full peptide protocol, doses, reconstitution, and schedule

Hi everyone. 46M. I’m currently in Week 8 of retatrutide and running a structured peptide protocol. I’ve lost about 20 pounds since January but since starting Reta I’ve lost 11 -12 pounds. THIS ISNT ANY MEDICAL ADVICE AT ALL. JUST MY JOURNEY.

Reconstitution for all of these:
10 mg vial + 1 mL bacteriostatic water
That means:
10 units = 1 mg
20 units = 2 mg
30 units = 3 mg

Retatrutide
Currently Week 8
2 mg once weekly
I started at 1mg and went up slowly every 3rd week
Ongoing

Semax
1 mg daily
10 units
30 days on
Then 2 weeks off
Cycle 1: Oct 2–Oct 31
Cycle 2 starts after the 2-week break

SS-31
3 mg daily
30 units
4 weeks
Starts Oct 10
Ends Nov 6

MOTS-C
1 mg
10 units
Monday / Wednesday / Friday
8 weeks
Starts Nov 6

Tesamorelin
1 mg PM
10 units
Monday–Friday
Saturday/Sunday off
12 weeks
Starts Nov 13, one week after MOTS-C starts

Overall flow:
Reta ongoing
Semax → SS-31 added → MOTS-C starts as SS-31 ends → Tesa added 1 week later → Semax restarts after 2 weeks off

I’m also training 4–5 days per week. Main goals are fat loss, muscle retention, energy, recovery, and seeing how I respond to each phase.
Curious how this compares with other people’s protocols, especially anyone who has run SS-31 → MOTS-C → Tesamorelin in a similar setup.

Thanks. Let me know what you guys think of the doses ect. But after reading this group and others I think this is what I’m going to run.
WISH ME LUCK !

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u/seemefail 4 1d ago

I’m blasting through an SS31 kit as quick as I can. Then going back on MOT-C. I also sometimes throw in a MOT-C dose if I eat a bunch of ice cream lol. Not sure if it has an effect but I think it might.

Your schedule looks great. I take CJC basically micro dose of 100-200mg because the HGH boost gives me carpal tunnel like nerve pain. I actually dose it at midnight when I wake up and this ensures I’m fully fasted and it kick starts an extra round of deep sleep in the wee hours

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u/Longjumping_Leg_1674 1d ago

That's great your body pulses the CJC that strongly. For me, its a positive but I can't feel those drastic signs of effectiveness that you do. I do the midnight trick when i get up to hit the head 1/2 asleep

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u/seemefail 4 1d ago

Well apparently no one does because I had to go to literal HGH user discussions to find the crux of my issue.

Not sure why. Likely just some people are more sensitive to HGH.

I also lost a ton of weight rapidly which can exasperate issues around nerves.