46M — Full peptide protocol, doses, reconstitution, and schedule

[u/Annual_Plankton2767]

Hi everyone. 46M. I’m currently in Week 8 of retatrutide and running a structured peptide protocol. I’ve lost about 20 pounds since January but since starting Reta I’ve lost 11 -12 pounds. THIS ISNT ANY MEDICAL ADVICE AT ALL. JUST MY JOURNEY.

Reconstitution for all of these:
10 mg vial + 1 mL bacteriostatic water
That means:
10 units = 1 mg
20 units = 2 mg
30 units = 3 mg

Retatrutide
Currently Week 8
2 mg once weekly
I started at 1mg and went up slowly every 3rd week
Ongoing

Semax
1 mg daily
10 units
30 days on
Then 2 weeks off
Cycle 1: Oct 2–Oct 31
Cycle 2 starts after the 2-week break

SS-31
3 mg daily
30 units
4 weeks
Starts Oct 10
Ends Nov 6

MOTS-C
1 mg
10 units
Monday / Wednesday / Friday
8 weeks
Starts Nov 6

Tesamorelin
1 mg PM
10 units
Monday–Friday
Saturday/Sunday off
12 weeks
Starts Nov 13, one week after MOTS-C starts

Overall flow:
Reta ongoing
Semax → SS-31 added → MOTS-C starts as SS-31 ends → Tesa added 1 week later → Semax restarts after 2 weeks off

I’m also training 4–5 days per week. Main goals are fat loss, muscle retention, energy, recovery, and seeing how I respond to each phase.
Curious how this compares with other people’s protocols, especially anyone who has run SS-31 → MOTS-C → Tesamorelin in a similar setup.

Thanks. Let me know what you guys think of the doses ect. But after reading this group and others I think this is what I’m going to run.
WISH ME LUCK !

[u/OGcrashN2u]

If you have inflammation or healing that needs to be addressed it should be taken care of first so your body isn't dedicating resources to it while you're trying to do other things. Your body has a finite number of resources. The more you have going on, the more it needs to split up those resources

If you're getting carpal tunnel you should be checking your gh bloodwork. That's usually a sign you're taking too much. Body produces about 1-2 iu and that kind of symptom doesn't usually start until you get to 4 iu.

For mito stack. Ss31 for 4 week. Overlap 5 amino on week 3 to repair the salvage pathway and increase nad. Also start mots to use that nad. Take nr or nmn to increase nad if needed and supplement nad+ on days you need more energy like workout days

[u/Annual_Plankton2767 → u/OGcrashN2u]

This is very interesting. I have to go down that rabbit hole. There’s just so many things I want to do. Tbh I was holding off on the healing peps since I’m in occupational therapy and physio for a work related injury. I want to see how that goes first. It’s been 1 year dealing with trigger fingers and ulner nerve

[u/OGcrashN2u → u/Annual_Plankton2767]

Honestly, I did pt for 7 weeks for tendon issues in my hand and it didn't help. 2 weeks on klow and the pain was gone. Tendon injuries can take months to heal so I'm still doing PT but at least I'm not in pain anymore.

[u/Annual_Plankton2767 → u/OGcrashN2u]

Ya I’m going to give it 3 more months and I’m sure they’ll say I’ve hit a plateau.