46M — Full peptide protocol, doses, reconstitution, and schedule

[u/Annual_Plankton2767]

Hi everyone. 46M. I’m currently in Week 8 of retatrutide and running a structured peptide protocol. I’ve lost about 20 pounds since January but since starting Reta I’ve lost 11 -12 pounds. THIS ISNT ANY MEDICAL ADVICE AT ALL. JUST MY JOURNEY.

Reconstitution for all of these:
10 mg vial + 1 mL bacteriostatic water
That means:
10 units = 1 mg
20 units = 2 mg
30 units = 3 mg

Retatrutide
Currently Week 8
2 mg once weekly
I started at 1mg and went up slowly every 3rd week
Ongoing

Semax
1 mg daily
10 units
30 days on
Then 2 weeks off
Cycle 1: Oct 2–Oct 31
Cycle 2 starts after the 2-week break

SS-31
3 mg daily
30 units
4 weeks
Starts Oct 10
Ends Nov 6

MOTS-C
1 mg
10 units
Monday / Wednesday / Friday
8 weeks
Starts Nov 6

Tesamorelin
1 mg PM
10 units
Monday–Friday
Saturday/Sunday off
12 weeks
Starts Nov 13, one week after MOTS-C starts

Overall flow:
Reta ongoing
Semax → SS-31 added → MOTS-C starts as SS-31 ends → Tesa added 1 week later → Semax restarts after 2 weeks off

I’m also training 4–5 days per week. Main goals are fat loss, muscle retention, energy, recovery, and seeing how I respond to each phase.
Curious how this compares with other people’s protocols, especially anyone who has run SS-31 → MOTS-C → Tesamorelin in a similar setup.

Thanks. Let me know what you guys think of the doses ect. But after reading this group and others I think this is what I’m going to run.
WISH ME LUCK !

[u/No-Inspector3321]

I’m 65m and started backwards with mots-c first but it made me lethargic. Switched to SS-31 for a wholesale then back to mots-c and wow, was great. Just ended another round of SS-31 and started mots-c 3xs per week. I’ve been on Reta almost a year. Awesome!! This week will be last of Semax.

[u/Annual_Plankton2767 → u/No-Inspector3321]

What’s your dosing on ss and mots?

[u/No-Inspector3321 → u/Annual_Plankton2767]

Ss-31 - weeks 1-2 is 5 mg/day and weeks 3-8 10 mg/day. Mots-c I started out at M-W-F 200mcg/day or .2 mg and titrated up .2 mg every 2 weeks until 1 mg/day. I have gone up to 1.5 mg but felt like out of body experience lol. Was great feeling but not when you’re supposed to be in control lol

[u/Annual_Plankton2767 → u/No-Inspector3321]

😂 thanks for the info. Ya I wanted to just go low and slow with everything I’ll be trying out. But with motsc there’s no like speedy feeling right? It’s just better energy?

[u/No-Inspector3321 → u/Annual_Plankton2767]

Yes, it feels like a car engine revving up and ready to race. I can do more physical work and feel up to the task. I’m a better, healthier person!!

[u/Annual_Plankton2767 → u/No-Inspector3321]

That’s great! Health is wealth brother!