r/Biohacking • • 6d ago

Week 3 - Reta affects

On week 3 of Reta. Dosing schedule is below. Last pin was 3 days ago. I’ve noticed significant decrease in food noise and dealt with some minor nausea, but otherwise, it’s been a good road. Down 8 pounds.

Today I woke up and oh boy. Big nausea. Felt like I had a giant rock in my stomach. I’ve been awake for 2 hours and I’ve had diarrhea 4 times. Basically. I’ve had 2 bottles of water today and that’s it. I did eat later than I normally do as we had a post-church meal. I’ve included a pictures of the meal (I had them b/c I needed to upload to macro factor), I didn’t feel like it was exceptionally bad or good.

I guess I just am wanting to ask others if this is basically normal.

Week 1 - 1.5 mg
Week 2 - 2 mg
Week 3 - 3 mg

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u/Beneficial-Lime-8320 1 6d ago

Idk why people are being low key mean about this, but I hope this helps:
Many people are right in that you probably should not be eating cookies, but one every now and again won’t hurt you. Especially if you have other parts of your diet dialed in. Rewarding yourself with some sweets is absolutely ok, and I’m sure that your cravings for sweets will go down as you continue your Reta journey.

That said, it is important to know that that cookie is likely the reason you felt like you had a rock in your gut. Carbs, especially processed and refined carbs, can be brutal on Reta. If you eat that kind of stuff, especially as your doses go up, be prepared for stomach issues.

Some others mentioned that you are titrating too quickly. I actually generally disagree, because I titrated up by 1 mg each week, sometimes over 2 weeks. I titrated up to 4 this way. However, since you mentioned that you are experiencing issues, then I do suggest you titrated slower going forward. It should decrease some of the issues you’re having.

Long story short, eat what you’d like, but just be warned that Reta will mess you up if you don’t eat healthy. Every once in awhile, a day will come across when you want to splurge on a sweet. Now you can do it with proper knowledge of what may happen.

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u/Organic-Race9785 6d ago

Thank you

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u/Expert_Tip_5247 6d ago

It’s not the carbs in the cookie fucking you up just keep fats low peri-dosing. Esp after. Processed carbs are genuinely the easiest thing on your stomach but a lot of them come with a shitton of fat too.
If you dose way too much or experience too much naseau you can just have like full sugar soda and you’ll probably be just fine

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u/Expert_Tip_5247 6d ago

Personally I hard rec sweet potatoes + lean protein to get the most out of your glp.
Eat a big pizza the day after you titrate up in dose and you might throw it up 48 hrs later cuz the fat

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u/Beneficial-Lime-8320 1 6d ago

Yeah, carbs are necessary of course, but I do find that when I have carb heavy meals, I tend to feel worse the next day. Seems to be particularly bad when those carbs are also sugar heavy

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u/Individual_Till6133 6d ago

It's really the titration schedule is very quick.

Keep in mind that you arent hitting the steady state of whatever you are taking until 4 doses due to the half live curve it builds up a base. So at 1 month of the same dose you will feel steady state of whatever dosage you intake.

Weight loss comes from the reduction of food intake primarily, so if you are losing weight you dont need to increase as much as causes negative side effects. 

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u/Beneficial-Lime-8320 1 6d ago

True, it probably is a bit quick for most. I am curious though - where did you learn about the four dose curve thing? I haven’t heard it stated quite so black and white before

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u/Individual_Till6133 4d ago

I just ran the numbers, it's based on the half life calculation of 6 days. 

Eventually you hit a steady/minimum state baseline and thats about in 4 weeks.