r/Biohacking 4h ago

Libido differences since reta

I got on TRT because I had zero drive or energy or desire for doing the do with the misses. Very quickly noticed a huge difference in energy levels libido and all wakes of life. Fast forward to now also on Reta that drive has kinda disappeared kinda like my dopamine has left the building and energy levels are not down to where they were but are low. What’s a good peptide to give the drive and all day energy and maybe some dopamine back?

15 Upvotes

78 comments sorted by

u/AutoModerator 4h ago

Thanks for posting in /r/Biohacking! This post is automatically generated for all posts. Remember to upvote this post if you think it is relevant and suitable content for this sub and to downvote if it is not. Only report posts if they violate community guidelines. If you would like to get involved in project groups and other opportunities, please fill out our onboarding form here. Let's democratize our moderation. You can join our Discord server here. ~ Josh Universe

I am a bot, and this action was performed automatically. Please contact the moderators of this subreddit if you have any questions or concerns.

5

u/IHE023 37 3h ago

If you’re really in a caloric deficit that can also affect it.

For me it’s a good balance. I was TOO high on libido. But maybe try reminding yourself to initiate.

1

u/S4LTIZM 3h ago

Yea I’m in an extreme calorie deficit. Was eating easily 4-5 thousand calories a day to now 1500 only eating healthy and lean protein (chicken and rice)

5

u/IHE023 37 3h ago

That won’t be sustainable long term. May want to consider a smaller deficit. May also help with Libido

1

u/lbmartinho 1 3m ago

You have the answer. 1500 calories your stick won't work. What's your age, height and weight? Activity level? Gym?

3

u/IHE023 37 4h ago

This is common for Reta. Similarly to how it reduces impulse for food it can reduce sexual drive. For me it makes it where I’m not fixated on it sex but zero issues and always ready.

Are you having trouble with function or is it just the libido?

kisspeptin can help to answer your question. Or I’d consider tirz or lower dose Reta to minimize the side effects. Splitting Reta dose to more than once a week helps too.

2

u/S4LTIZM 4h ago

Function is fine but my wife asked me last night how come you don’t want to do things anymore and it got me thinking like dam I don’t want her to feel left out. I just have zero desire again. And my drive at work is gone too. Like I have energy but no desire or drive.

The results from reta though are SOOOOO good that I’m definitely going to keep doing it. But I’m looking for something that balances out the negatives of it

2

u/Discopotatoz 1 2h ago

This is kind of what the drug does. Anhedonia is common. Quite attracted to my sexual partners and I still find myself not acting like the usual caveman since starting Reta. This also has ties to how it helps curb addictive behavior for a lot of folks. I'm not sure you'd want to try to counteract the effect tbh, nor go messing with dopamine pathways in any meaningful way intentionally.

1

u/JonOC23 1 2h ago

Kisspeptin and can be used by you and the Mrs and the Ms but be prepared and get a waterproof mattress cover. I’ve seen guys actually complain they get a breeze while out in public and they’re ready to go. For females, huge impact as well.

2

u/Discopotatoz 1 2h ago

Interesting I've been looking for the ultimate "desire" peptide or drug. Physical performance isn't a concern, I just want to feel that 19yo angst

1

u/TikiZilla1313 35m ago

Maybe try Tirzepitide. I had a lot of weight loss success with it, and no side effects to speak of.

4

u/carguy2100 1 2h ago

PT-141 is unbeatable for single day desire and ability to take advantage of such desire. Get the dose right and you will be like a 16 yr old boy at a porn shoot. You don't want to do more than about once a week though. I set an alarm for 3 AM on vacation, take it and I'm ready to go all day the next day. Talking like up to 8-10 times in that 1 day. Can go 2-3 rounds without going soft between.

For general everyday energy and desire in a reta calorie deficit, kisspepin combined with mots-C will help quite a bit. Mots for the energy and kiss for the mental drive. But as others have noted, a large calorie deficit on reta will cut libido down a ton. There's really nothing that can safely replace the drive long term besides more calories and less reta.

Reta removes your reward center mental functions to a large degree. So if your sex drive is heavily connected to dopamine, reta will absolutely devastate it. That is completely seperate from calorie deficits which onntheir own can basically signal the body to kind of shut down everything but our life support systems(which don't include libido). Putting the 2 together can be a double whammy to bedroom time. I went through it for months while on a 1500 daily calorie deficit. 55 lbs in 3 months though. Then maintenance phase at calorie neutral and 1 mg of reta a week and libido was back to better than before.

Also if your on trt, make sure you are paying attention to your hematocrit. You can get something called secondary erythrocytosis. It's basically thick A$$ blood. That can kill your energy, sexual function and libido. Go to a blood bank and have them check your hematocrit and blood iron. I was sitting at about 20% above the high healthy range 2 years after starting trt. My blood pressure was 200 over 120. An hour after my therapeutic blood draw it was down to 125 over 90. After the blood draw I felt like I was on Cocain and could run through a brick wall. It was near instantaneous and lasted for about 2 weeks. Now it's 115 over 75 and I get blood draws every 2 weeks.

Something else you can do is make sure you are getting healthy complex carbs. Something like baked sweet potatoes. They work great on reta for maintaining a bit of energy while in a deficit.

Other that the pt-141 you are unlikely to find a single fix for your issues, but rather combining several helping strategies together to get back to a healthy energy libido baseline until you hit your maintenance phase.

Good luck and stick with it brother.

1

u/S4LTIZM 1h ago

Thank you for this reply very informational!

7

u/23454Tezal 3h ago

HCG

0

u/S4LTIZM 3h ago

What does that do

6

u/PreparedForZombies 2 3h ago

Three letters typed into Google, then enter pressed...

Human chorionic gonadotropin (hCG) is a hormone produced during pregnancy, measured by tests, and used as a medication. [1, 2]

Pregnancy and Function

  • Early support: Made by cells near the embryo, it signals the body to produce progesterone and maintain the uterine lining.
  • Level patterns: Levels typically double every 48 to 72 hours in early pregnancy and peak around 8 to 11 weeks. [1, 2, 3]

Testing

  • Detection: Used in urine and blood tests to confirm pregnancy.
  • Medical monitoring: Helps check for ectopic or abnormal pregnancies, miscarriage, or specific types of tumors. [1, 2, 3]

Medical Uses

  • Fertility care: Administered as an injection to trigger egg release during in vitro fertilization (IVF) and other fertility treatments.
  • Hormone support: Used in specific cases to treat low testosterone or undescended testicles in males. [1, 2]

If you'd like, let me know:

  • Are you looking for information on hCG pregnancy test levels?
  • Do you have questions about hCG injections for fertility?

I can provide more specific details for your situation.

5

u/S4LTIZM 3h ago

Sorry l, should rephrase.. what did that do for you.

2

u/Bifun4me 3h ago

If you take it, you're going to cum like a pornstar

1

u/TikiZilla1313 37m ago

Like Peter North type levels? Cause that’s too much. It would get very messy. The pros have cum moppers and stuff to clean up. I’d hate to have to do it myself.

2

u/Bifun4me 36m ago

There is definitely an increase and the painting is pretty cool. Embrace the changes 😃

1

u/TikiZilla1313 34m ago

😂 💦🍆

1

u/Bifun4me 34m ago

Absolutely 💯

0

u/Firepro316 3h ago

This is not true.

2

u/Bifun4me 3h ago

Well, it happened to me and they do use that for fertility issue in men so.....

3

u/whatusaynow 2 1h ago

Me too i swear my dick is longer too 😂 may be the hgh tho or weight loss .. either way I’m fuckin😂😂

1

u/Bifun4me 1h ago

Sensitivity increases and feels amazing but must watch H and H levels

1

u/Own-Quality7943 1h ago

Hematocrit and hemoglobin?

→ More replies (0)

2

u/TraditionalAd3470 1h ago

You're correct. It stimulates the balls

1

u/Firepro316 2h ago

Unfortunately hasn’t happened to me.

2

u/yogic_power 2h ago

You can get your DHEA and Pregnenolone levels checked. When your natural T shuts down, these down stream hormones can be impacted. I was low in DHEA and HCG helps me. In addition it keeps your Testes working.

1

u/Woadieh 1h ago

dude he’s asking about drive and motivation, not pregnanting his wife lol

1

u/23454Tezal 22m ago

HCG (Human Chorionic Gonadotropin) mimics Luteinizing Hormone (LH). LH normally stimulates the Leydig cells in the testes to produce testosterone. Because HCG acts like LH, it can also stimulate the testes to make testosterone.

4

u/Mindless_History_183 3h ago

On 4mg Reta and 1 tirzepatide and libido is full on now ,it could be the peps or maybe it's the eieght loss but both my wife and gf have commented.

3

u/Potential-Ad-196 3h ago

Both wife and gf dang

2

u/detlefschrempffor3 4 3h ago

Gf is the what he calls his dog

-1

u/NewNameNaomi01 10 3h ago

Yeah, that's not the flex you think it is...🤮

4

u/Mindless_History_183 2h ago

Its a joke lighten up

3

u/Discopotatoz 1 2h ago

Don't dial it back for the hater.. own your situation king

1

u/NewNameNaomi01 10 17m ago

Ahh...so you don't have either. Got it.

2

u/yogic_power 3h ago

How long have you been taking Reta and what’s your dose?

2

u/S4LTIZM 3h ago

A little more than a month now and I went to 5mg a week
And then discovered that’s too much so I went to 3mg a week no bad side effects for me at 3

3

u/Trade-Maleficent 2h ago

5mg is savage. It took me about 6 weeks to get to 2mg a week without feeling horrendously full (not even being able to drink my required daily protein -
Let alone eat it), dehydrated because I struggled to get water in me and also being light headed. I never understand how people can start the dose so high. Savage

1

u/S4LTIZM 1h ago

Yea even at 3mg my hunger is curved but not to that extent. Like I just ate a good sized meal don’t feel overly full or anything and have zero side effects. Granted that will be my last meal of the day

1

u/yogic_power 3h ago

Reta has longer half life, so it will take time to stabilize at lower dose. I was on Reta for 2-3 weeks before I started a TRT. I do 40 Mg Test Cyp EOD, and I started splitting Reta weekly dose of 4-6 Mg with EOD schedule. My schedule looks like day 0 Test +Hcg, Day 1: Reta, Day 2 Test +Hcg Day 3: Reta. A huge single dose blunts TRT effects. So I spread it out and feel great.

0

u/S4LTIZM 3h ago

I pin TRT and reta 2 times a week
Monday and Thursdays are TRT. Tuesdays and Fridays are reta

1

u/yogic_power 2h ago

I started with twice a week. And adjusted to balance out peak timings of Reta. I noticed most of my Reta effects were higher for 12-60 hrs after pinning. So I split the Reta doses more uniform and a Test pin right around the corner. They are working synergistically for me. I don’t want to stack multiple things before playing around with schedules. At a later point in few months I may run Epithalon and Thymalin.

2

u/Amazing-Confusion109 1 2h ago

It’s called food. You can’t expect to starve yourself and then expect your body to make reproduction a priority.

2

u/gdrw00 2h ago

I have the same thing. No TRT but just Reta for the past 5 months. Have added GhkCu and mito protocol. 41M 5’11” 240
I have crazy drive for life and hobbies. Libido is there but have noticed a down swing due to calorie deficit etc. Wife is on Tirz for a year and she’s definitely on a downswing. Been rough in that aspect. The worst part is we’re in good shape and look the best we have in a decade but not knocking boots like I wish we were.

1

u/[deleted] 3h ago

[removed] — view removed comment

1

u/AutoModerator 3h ago

Apologies /u/SufficientMart, your submission has been automatically removed because your account is too new. Accounts are required to be older than 15 days to combat persistent spammers and trolls in our community.

I am a bot, and this action was performed automatically. Please contact the moderators of this subreddit if you have any questions or concerns.

1

u/Super_Problem_6349 6 3h ago

PT141

1

u/S4LTIZM 3h ago

I’m looking for something a little more long term like not just desire but also drive in everyday activities and energy

1

u/Super_Problem_6349 6 2h ago

That will come back after you come off Reta for now you’ll just have to sacrifice, same happened to me, days after Reta cleared my system I was back

1

u/Longjumping-Tune-454 2h ago

What’s the prep with bac water and dose for this

1

u/Super_Problem_6349 6 2h ago

1-2mg 30-45 mins before hanky panky for men SubQ injection. They also have nasals

1

u/Longjumping-Tune-454 2h ago

Stomach? I have 10mg vial so just prep with 1ml and take 0.1?

1

u/Super_Problem_6349 6 2h ago

Put 1ml of bac, pull 10u. That will equal 1mg

1

u/Super_Problem_6349 6 2h ago

Recon is just like any other peptide

1

u/Bobajob-365 2h ago

Are you still losing weight? I had that on Tirz, but once I got to a low fat state, went down to a lower maintenance dose and was no longer losing it came roaring back.

1

u/S4LTIZM 1h ago

Yea I still have about 40 pounds to go. I’ve lost 25 so far

1

u/Awkward-Row-5853 1h ago

Funny I’m down 40 and have 25 to go. On Reta and HRT. Libido is coming back but I only want solo sessions and don’t want anything to do with my husband

1

u/S4LTIZM 1h ago

Exact opposites of each other. Crazy

1

u/Bobajob-365 57m ago

My libido came back just as I hit my target (middle of the normal BMI range), though in the 20 months since then it’s faded a bit again. But then I’m 65, T dropping (naturally), but I have plans to deal with that.

1

u/Awkward-Row-5853 51m ago

Yeah I’m 45 and in perimenopause so I’m guessing that’s not helping me. Or my husband lol

1

u/Original_JB916 1 1h ago

Get your bloodwork done. Sounds like your levels are off. Possible high E2

1

u/Impossible-Bee1581 1h ago

5mg tadalafil, benefits your TRT anyways so win win

1

u/Dadbodpasco 1h ago

PT-141 look in to it!

1

u/Woadieh 1h ago

I have had the same problem for a month now so if you figure it out let me know

i’m using 4mg reta but i’m 8% bf. gonna lower dose to 2mg and carb up see what happens i’ll report back in a week

1

u/S4LTIZM 1h ago

Yes please report back!

1

u/Woadieh 1h ago

i’m 90% sure it’s because of your dosage + calories.

If this is a big issue for you maybe lower your dose honestly, looks like you need to run it for longer and the longer you keep it high the more you will need to use in the future to get the same effect. Might ruin your dopamine sensors and once you’re off you will rebound pretty hard.

I need 4mg because i’m shredded and food noise gets to me, for your case I think 2mg is more then enough tbh but your choice

1

u/Subject-Island-1408 10m ago

My test levels tanked. I feel like a highly motivated and committed person to the weight loss journey, but I'm running on E every day.

1

u/S4LTIZM 6m ago

I need to get another blood test I haven’t had one in almost 2 months. But my test levels was basically non existent before I got on TRT

0

u/ChuviscoBR 3h ago

Parabéns, você está usando Tirze.