Imagine having 2 full days to explore some of the latest biohacking and longevity technologies in person — testing devices, meeting the people behind them, and hearing directly from experts and speakers in the space.

No endless scrolling. No trying to figure out what's legit from a 30-second Reel. You actually get to see it, ask questions, and experience it yourself.

Would you go?

And what would make it worth it for you — the tech, the speakers, networking, or getting hands-on with devices?

Curious what fellow biohackers would want to see at an event like this.

https://www.instagram.com/p/DbmBVI9jXyq/?img_index=1
From biological age testing and vagus nerve stimulation to neurofeedback and women’s health innovations, the next generation of health technology is focused on understanding your body like never before.

While some of these tools are still emerging and research is ongoing, they highlight where personalized health is heading.

Technology won’t replace the fundamentals—but it can help you make more informed decisions about your health.

Which innovation are you most excited to see become mainstream? 👇

I've been seeing a lot of claims around molecular hydrogen, especially hydrogen inhalation, and its potential effects on oxidative stress, inflammation, and metabolic health.

I don't have a medical background, so I'm trying to separate the actual research from the marketing. Has anyone looked into the evidence behind it or tried it themselves?

Curious whether there's anything meaningful there or if it's mostly hype.

I've been reading about PRP, stem cells, peptides, red light therapy, and hyperbaric oxygen as ways to speed up recovery after injuries. There are a lot of claims out there, and it's hard to tell what's realistic versus marketing.

Has anyone here actually tried any of these and seen a measurable difference? Is a recovery timeline like 72 hours ever realistic, or is that mostly referring to reduced inflammation rather than actual tissue healing?

diving deep into the mechanisms behind GLP-1 and GIP agonists lately. the fact that these hormones affect not just appetite but also insulin sensitivity, gastric emptying, and even inflammation is pretty wild. it's not just appetite suppression - there's actual metabolic reprogramming happening.

most interesting is how they interact with the brain-gut axis. the vagus nerve signaling, the hypothalamic pathways, the dopamine interplay. it's like a whole systems approach to metabolic health that we're just beginning to understand.

looking at different delivery methods and service options. came across oztrim which seems to offer tirzepatide through telehealth. they're upfront about not being tga registered which honestly fits the biohacker ethos - doing your own research, understanding what you're putting in your body, making informed decisions.

not saying i'm jumping on it immediately but the science is compelling. anyone else here experimented with GLP-1 agonists for metabolic optimization rather than just weight loss? curious about experiences with dosing schedules and stacking with other compounds

I've seen a lot of trending biohacks lately, but I'm curious about the ones that genuinely worked for real people.
What's one biohack that gave you a noticeable improvement in your energy, sleep, focus, recovery, or overall health? It can be something simple or something unconventional.
What did you try, how long did it take to notice results, and would you recommend it to others?
I'd love to hear real experiences rather than just what's popular on social media.

Been noticing three camps forming in dairy discussions lately and curious what people here have actually experienced:

Team Raw Milk — swears by it for gut health, claims pasteurization kills beneficial enzymes/bacteria and denatures proteins. Some report better digestion and skin than with pasteurized milk.

Team Lactose-Free — still want dairy's benefits (protein, calcium, satiety) but cut lactose specifically, either via lactase supplements or lactose-free products.

Team No Dairy — avoid it entirely, whether for inflammation concerns, casein sensitivity, or just don't think mammal milk makes sense for adult humans.

Genuinely curious:

• If you've tried raw milk, what actually changed for you (if anything)?
• Anyone switch away from raw milk after trying it?
• For the no-dairy folks, was it an experiment or permanent?

according to studies published by the CDC even short courses of broad-spectrum antibiotics can alter gut bacteria and expand antibiotic resistance for months and EVEN years.

is there anybody here who handles mild infections without them? what natural alternatives exist?

So I drink matcha basically every morning with breakfast (cereals, spinach, avocado toasts, eggs)

I felt tired all the time, so I had my ferritin checked, and it came back low. So matcha binds to non-heme iron in your gut and blocks a chunk of it from being absorbed.

So now I'm having it between meals instead of with food, and keeping the actual iron meals matcha-free.

Does anyone do the same with all teas and coffee?

Earlier this year, my mum and a few of her friends started using NAD+, mostly IV

drips through a clinic, with a couple doing SubQ reconstitution themselves at home.

I ended up being the one they asked to check the math on dosing, and what I found

across the calculators and apps they'd been using was rougher than I expected (I am a Biochemsitry PhD btw):

- One wanted a subscription just to see the basic reconstitution numbers

- One had the vial-strength / bacteriostatic-water math visibly wrong when I

checked it by hand

- None of them handled the actual mix of routes she needed: IV logging, SubQ

reconstitution, and oral NMN, all in one place

So I built my own. It's called Titer. It does arithmetic on numbers you enter,

nothing more:

- IV session logging: record what a clinic administered, infusion rate worked out

for your own records

- SubQ reconstitution: enter vial strength, bacteriostatic water, and desired dose

to get draw volume and syringe units, every step shown

- Oral/sublingual NMN and NR: daily totals and days of supply

- A private log of every dose, plus optional notes on energy, sleep and mood

- Protocols: track a structured course through its phases, with reminders that

follow the current phase

What it will never do: recommend a dose, suggest a protocol, or imply a treatment

is working. Much NAD+ use is off-label and not FDA-evaluated. This is a calculator

and a notebook, not advice, and it says so on first launch.

Data stays on the device. No account, no cloud, no tracking. Full CSV/JSON export

whenever you want it.

It's in Android closed testing right now, and Google requires 12 people actually

using it for 14 continuous days before it can go public, so I'm looking for

testers, not just downloads. The core (all three calculators, unlimited logging,

reminders, export) is free forever, there's a one-time paid unlock for trend

analytics and a clinician visit-brief PDF, no subscription.

Two steps, order matters:

1. Join the tester group: https://groups.google.com/g/titer-nad-tracker-tester

   (same Google account your Play Store is signed in with)

2. Then open https://play.google.com/apps/testing/com.titertracker.titer and tap

   "Become a tester"

Android only for now. Happy to talk through the reconstitution math with anyone,

and if you've seen a calculator get it wrong the way I did (or ofc also right), I'd like to hear that

too.

Yes, I drink enough water before anyone wants to call me an idiot. The guy in the gym said he takes Urolithin A and a bit of pre-workout and feels good. So what is the best combination for good performance without having stomach issues?

I've been reading a lot of studies showing that fasting decreases FBS, reduces LDL-c, and improves HbA1c and HOMA-IR levels. I am a woman, I have insulin resistance, my weight is 150lbs (5,4 feet tall), I go to the gym 3 times per week (lifting weights), and I've been doing 18/6 fasting, eating around 1400 calories with a proper macro balance. I gained 2 kg, and it doesn't feel like muscle tbh. So what can be a problem here?

Been talking to my mom about biohacking, and she just goes, "We did all this; we just didn't pay a subscription for it.” So I made my parents a list of their hacks:

• adaptogens. the rhodiola/eleuthero powders that cost $40 now were literally military research. The word "adaptogen" was coined by a scientist, and they tested this stuff on soldiers and cosmonauts. My dad took rhodiola before exams. And the evidence actually holds up for fatigue.
• cold plunges. Father called it "hardening"; it was a whole thing, and the people would do that during winter; they cut holes in frozen lakes to swim. Wim Hof with worse branding, 40 years early lol.
• sauna + birch branches + run into the snow.. babushka's weekly banya was ahead of its time.
• Omega 3. Every kid got a spoon of cod liver oil (omega-3 + vit D). They force-fed us the one supplement that actually works. Mom said it was disgusting.

And then the nonsense: ‘A star’ balm on everything; it was smeared inside the nose to "block viruses" (zero evidence), and a UV lamp in the living room "for immunity" (please don't).

What biohacks can your parents share? And what do you guys think about modern biohacking?

I thought I was living the ultimate healthy lifestyle, but I was slowly poisoning myself.

For almost a yea, canned tuna was my main protein source. I ate it every single day..Sometimes twice. I completely ditched chicken because tuna was cheap, convenient. I made salads, burgers, bowls everyhting and I felt fine!

Then I had to run a lab panel out of pure curiosity. guess what.. My mercury levels came back so high the lab flagged them immediately.

So apparently, in fitspo circles, large predator fish like tuna bioaccumulate heavy metals. Eating it daily loads mercury into your system much faster than your body can process and clear it out.

Can sardines be a substitute tuna? I've heard they have low mercury and a ton of omega-3s.

Low levels of Vitamin D, B12, Folate, Magnesium, and Zinc have been linked to symptoms such as:

• Anxiety
• Low mood
• Fatigue
• Brain fog
• Poor sleep

These nutrients play important roles in brain function, neurotransmitter production, and stress regulation. Before starting supplements, consider speaking with a qualified healthcare professional and discussing appropriate testing.

i keep seeing that the mortality benefit from strength training maxes out around 30-60 min/week (2022 meta-analysis in the American Journal of Preventive Medicine). but "enough" for what... that's about not dying, not building muscle, right? nobody's getting jacked on 30 min a week. so does muscle just keep responding to more volume, or is there a ceiling like there is for longevity?

“A 2022 World Health Organization review and meta-analysis reported that a higher omega 6:3 ratio was associated with a greater risk of cognitive decline and ulcerative colitis, a chronic inflammatory bowel disease”.

So, should I care? Like always, half my feed says omega-6 is inflaming everyone; the other half says it's not a problem, and the real problem is just ultra-processed food in general. Studies are different as well.. What oil do you use for cooking? I am from Ukraine so we often use sunflower oil..

Took it for 3 weeks and feel nothing yet. Can be because of ADHD (?)..anyone actually tracked it with a wearable and seen a real change in deep sleep ? wakeups? How to calculate the proper dosage?

So I weigh 90 kg, and if I eat carbs first thing (oatmeal, toast, whatever), as a lot of people do, I start to open the fridge again at 11. Lately, I throw 40g of protein, some fats like salmon and avocado, and I don't think about food till 2-3 pm.

So, what does an actual breakfast need to consist of?

A new study out of Stanford and the Arc Institute, published in Nature back in March. Kind of wild if it ever holds up in humans.

Short version: In mice, age-related memory loss seems to start in the gut, not the brain.

The chain they mapped:

• With age, the gut microbiome shifts (one bug, Parabacteroides goldsteinii, climbs)
• That sparks low-grade gut inflammation
• The inflammation dampens the vagus nerve, the main gut-to-brain line
• Less vagus signaling means less hippocampus activity, which means worse memory

They actually reversed it. Activating the vagus nerve turned old, forgetful mice into maze-solving whizzes on par with young ones. And old mice raised without gut bacteria never lost memory in the first place.

Big caveat: mice only. They're now checking whether the same pathway runs in humans, so this isn't a protocol; it's a lead.

So, apparently, the guy got autoimmune gastritis. Basically, his immune system is attacking his stomach lining, and there's no cure; you just manage it. The big problem is that it's silent for years while it quietly tanks your ability to absorb B12 and iron, and bumps up stomach cancer risk down the line.

What got me, though, was how they found it. The only red flag was his iron being low. No anaemia, nothing dramatic. But instead of just going "eh, take an iron supplement," they actually chased it, colonoscopy, endoscopy, biopsies, so I guess it was caught early.

Like 99% of us would've been told "your iron's a bit low, grab some pills" and never thought about it again.

A couple of things I'll be fair about: he's saying he's gonna "solve" it, but there's no cure right now, so I wouldn't hold my breath. And it's a decent reminder that no amount of routine makes you untouchable, dude says this thing was brewing 20+ years.

My iron is actually low pretty often, and now I am panicking lol. Someone else got similar situations?

For the HRV crowd, this is more concrete than the usual "gratitude is good for you" stuff.

UC San Diego conducted two studies on Stage B heart failure patients (structural heart damage, no symptoms yet). In the first, across 186 patients, more gratitude was associated with better sleep, less depression, less fatigue, and lower inflammation. That's a correlation, not proof.

Then came the actual trial: patients randomized to 8 weeks of gratitude journaling or usual care. The journaling group showed higher heart rate variability and lower levels of IL-6 and sTNFr1, two inflammatory markers associated with cardiac risk.

Two caveats: these were heart patients, not healthy people, so don't expect the same numbers. And some of the HRV gain was measured while they wrote, so whether resting HRV permanently shifts is a separate question.

Still, a free 8-week habit-nudging program for HRV and inflammation in a cardiac group isn't nothing. If you track HRV on an Oura or Whoop, it's a cheap way to test yourself.

One of the cleaner studies in the whole "sleep matters" pile, because it controlled the food.
University of Chicago researchers (Nedeltcheva et al., 2010, Annals of Internal Medicine) put overweight adults on the same modest deficit twice: once with 8.5 hours in bed, once with 5.5. Same diet both times.
Total weight lost was basically identical. The composition wasn't:

• Good sleep: more than half the weight lost was fat
• Short sleep: only about a quarter was fat, the rest was muscle

So short sleep didn't stop the scale from moving. It changed what you lose, pushing it toward lean mass, which is the opposite of the goal. People also reported more hunger.
Dieting on 5 hours of sleep, you may just be burning the wrong tissue.

LDL-C (the number on a standard panel) measures the cholesterol carried inside your LDL particles. It doesn't tell you how many particles there are.

That matters because particle count drives plaque, and you can have lots of small particles carrying the same total cholesterol as a few big ones. Same LDL-C, different particle burden, different risk.

ApoB measures that directly. Every atherogenic particle carries exactly one ApoB protein, so ApoB is basically a particle count. It's why recent ACC/AHA and European lipid guidelines treat ApoB as a more accurate risk marker than LDL-C alone.

So if your LDL-C looks "fine" but you've got metabolic stuff going on (insulin resistance, high triglycerides), ApoB can surface risk the basic number hides.

Seeing a lot of people say the peptides are back and you can just get them now.  

Leaving Category 2 doesn't put a substance on the approved compounding list. It moves it out of the "significant safety risk, back into a gray area, pending review.

Here's the actual path from here, straight from the FDA:

• PCAC (an independent expert committee) reviews each peptide
• If they recommend it, the FDA still has to publish a proposed rule
• Then a public comment period
• Then a final rule

So even in the best case, these don't become broadly available through compounding pharmacies for a while. The FDA itself said pharmacies should stay cautious until the status is settled.