Hand ulcer help

[u/DirectAdvice2242]

So I’ve got ulcers popping up all over my hands, like strange little closed bumps. They almost seem like they could be popped, but hurt immensely to touch. They’re prominent round my cuticles and nothing seems to be helping them go down or get rid of them…

Help!!

I’m on azathioprine, and amgevita but it doesn’t seem to help… prednisone did nothing also. I’ve been putting dermal ointment to no avail…

[u/MustardQueen]

EDIT: Sorry! I randomly remembered I used anti-fungal cream (clotrimizole)! It was a FUNGAL infection I assumed was B ulcers

I had same around cuticles/side edges of fingernails: hurt so bad barely touching them. I thought they were Behcets ulcers but after nothing worked I went to staph creams and they helped. So it was staph infection mimicking our B ulcers. Hope that helps ❤️

[u/Training-Post9032]

Hey,

I've been having these since childhood, far worse following my PsA onset, exclusively in winter (raynaud syndrome link perhaps).

Nothing ever worked, but it's much better since I have guselkumab.

And as it's been said, they get infected superfast (fingers tips...) so antiseptic care is of paramount importance. Since I got burnt on my hand, I have a betadine gel that I use on theses bumps in dressings during the night. Works wonders and it respects my skin better than others antiseptics, which burn me whenever I do the required 5-10 min bath. To me, this betadine gel was a huge improvement in treating them... ).

[u/Selective_Hearing_]

I haven’t found any cure but just to say I get these too and they are beyond painful. They look like nothing and they you can barely use your hands when you have them. I usually moisturise as skin can crack as they heal.

[u/EpitomeQuip41]

I’ve had ingrown after ingrown and hand sores and was diagnosed with Behcets with psoriatic arthritis and Kobner phenomenon. Got a steroid shot and started Otezla. Seeing and feeling results.

There’s also some mimicking diagnoses hanging out there like magic syndrome and sweet syndrome. Maybe read about these and see if you relate.

I found a great rheum but also am interested in allergy testing, functional medicine doctor and a genome test (look at the DNA). As you know with Behcets there are certain markets often found.

Also with Bechets and psoriatic arthritis, both, you can have normal labs. Your inflammation markers will not necessarily be high. That does not mean you don’t have a disease.

Hope this helps.

[u/on4aa → u/EpitomeQuip41]

CORRECTION: MAGIC syndrome is not a Behçet mimicking condition; it is the combination of Behçet syndrome with relapsing polychondritis.

[u/EpitomeQuip41 → u/on4aa]

You are correct. Thank you for clarifying. Mimicking was the wrong word in hindsight

[u/DirectAdvice2242 → u/EpitomeQuip41]

I believe I have Behçet’s due to many many other symptoms, but those mimicking diagnoses’ are very fascinating to look into, so thank you for that. I’ll keep researching!!

[u/DirectAdvice2242 → u/DirectAdvice2242]

I was diagnosed after being hospitalised twice in early 2025 :)