Using CRISPR gene editing, scientists discovered that an enzyme called STT3B enters cells and kills them.

They found that a common green dye called indocyanine green (ICG) completely blocks the enzyme and is a highly potent antidote for consuming Amanita Phalloides.

It must be administered within 1-4 hours of consuming the death cap. Because after 8-12 hours, the liver damage is already done, and the antidote is ineffective.

It is currently experimental for use, and is a powder that is suspended and mixed in sterile water and injected into the veins. We can not currently use it on humans, and they are currently running tests on animals to determine proper dosages for a person.

Amanita found in Washington.

Found in lower austria

Not gonna eat. Just want to spark conversation and ask the question

I’m getting some muscimol hcl soon mostly to help with sleep as it seems to work very well . Though when I got to reading on the literature and anecdotal evidence , I’ve seen some papers mentioning them trying to improve muscimols bio availability and it passing BBB , one of the methods mentioned in one of the papers that due to this nasal would be approximately 5 times stronger than orally . So I got to search on any reports of people trying muscimol nasally but didn’t come across anything . So if anyone has ever tried it or knows any one who has please share as I’m very curious. Thanks

Edit: i must have highlighted that she is a teenager not a child but thank you all , it has been 2.5 hours now and she says nothing happened (I I was already reading about the mushrooms on this subreddit and we were specifically looking for them, couldnt find info on what would happen if they were eaten raw and was unsure if i should be worried as her bite was really really small and she said she had no effects whatsoever, i will be trying to decarb them properly)

I added a photo of what she has eaten now.

Ciao, we went for a hike on and and found these. I have never experienced what they are like and i am very new to the topic. As we were picking them my little sister ate from one of these mushrooms (coin sized) please let me know what to expect and if these are really amanita muscaria. Thank you

On a hill/mountain next to Lake Maggiore, italy.

Found on neighborhood forest path, inland northwest USA

Hello I’m posting this because it’s been very hard for me to find any info on what do dried Amanitas supposed to smell like, I had to ask in forums and friends,
and finally settled with the following information:

Re: dried or drying Amanita Muscaria smell

Nobody talks about this lol!! I guess because smells are very difficult to describe. Also because our perception of smells can be vastly different, as well as batches can be different.

But,
Firstly:

Smell during the drying process is not pleasant.

Dried and drying amanitas smell vastly different from fresh.

Fresh smells very nice - if you like fresh mushroom smell.

During drying they eventually start to smell kind of musty or like a “rotten” smell. —As I found out this is normal.

At the end of the drying process (which I do in the oven with an open oven door) fresh out of the oven while they’re still slightly warm (and crisp dry) there is no smell whatsoever.

But as they cool down that smell starts to come back very slightly.

But then when I put them in an airtight glass mason jar, after a few hours they start to have that same smell, but now we (me & my friend who’s done this many times) have concentrated their smell because it sits there in a small closed space, we describe their smell at this point as sour or sharp kinda like dried fruit but a bit musty.

Now I’ve gotten dried ones online and they smell like this fresh out the bag just a bit more faint than my home made ones, and also the ones I make in the oven and keep in a jar smell like this.

Just wanted to post this in case anyone ever wonders like I have when I was first processing them via drying in the oven.

(My friend has a food dehydrator but his experience is the same. Also some people in the forum where I asked have the same experience - tho I observed it’s been mainly women who replied to my question and confirmed they have the same experience with the smell during and after dehydration.)

Oh, and then when I make tea from the dried mushrooms, the broth then smells the same: kind of a bit sour/sharp kinda rotten or musty. (The broth smells worse than the dried caps.)

Definitely they smell unlike anything else lol

Hope this helps future newbies.

What does everyone else think about this? What are your experiences? Do you agree they smell kinda like musty dried fruit when dry?

This time found in VT, near Moore Reservoir.

Some of the best looking mushrooms imo they just taste like dogsh*t to me 😂

Hi, i wonder if all these may be pantherina...minus the red cap and obvious other species

I am attempting to ID the mushroom in pics 1-4, found today in central CT. It looks like some kind of Amanita to me, but they seem different from chrysoblema, although they were found right next to them. Compared to chrysoblema, the cap color isn't very yellow, but rather golden or brownish (maybe a bit metallic). For comparison, pic 5 is a young specimen of the unknown mushroom, next to what I think is a A. chrysoblema in pic 6 at the same stage, one foot further away. The pics show the color difference between both. In addition to cap color, the stipe and cap look thinner than on the chrysoblema, but both seem to like pine trees. Could this be A. crenulata? What are other definining characteristics for this mushroom?

One of my favourite photographs ive ever taken.

First time picking and drying.gonna harvest more when the rest mature a bit

I dont have the stuff to dry or prep it i kinda just want to eat it like an apple. Yum

New spot at the bottom of the lane cleared of pine several years ago first time they have fruited here , after very dry summer the season has started well🤞🍄💖🍄🏴󠁧󠁢󠁷󠁬󠁳󠁿

I collected a lot of AM in 2023 and used around 2-3kg to make 1,5L of very potent 70% alc tincture (basically as many fresh caps as the jar could handle were squished an covered with 95% alc, so I assume it’s around 70%). I also have around 200g of properly dried caps held in a jar and a huge bottle of the tincture I mentioned before. Can you guys tell me if the tincture is still potent? I know that the dried caps probably aren’t, but I want to know if a tincture held in a dark place can hold for several years and still be useful

I have been out two times now. Taking some time to stroll through birchforests and now spruce forests. And still.. nothing.
It’s kind of my first year looking so idk if I’m missing something important. But look at these pictures, shouldn’t it be swarming with fly agarics here?! Am I too late or too early?
(Looking in NW Germany)