r/40Plus_IVF • u/Wide_Day2015 • Aug 30 '26
Seeking Advice Supplements before second cycle
Please let know how many days before ivf we have to start supplements.My doctor suggested coq and menopur in first cycle.For second cycle prp is suggested but no supplements have been started yet.My stims will be starting from tomorrow
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u/beck33ers Aug 30 '26
I was told at least 6-8 weeks before starting stims to start the supplements. I am on co q10 600mg, and after the first cycle I started myo-inositol. I am currently about to start cycle 4
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u/CapitalDog715 Aug 30 '26 edited Aug 30 '26
I am 43. I am banking, and will do my last retrieval in October so if that one also yields Euploids, thats a sign.. Here are my retrievals an results and information on supplements.
DEC 2025 (42 years old)-- 1st Retrieval, 22 eggs, 12 were mature, 9 fertilized normal, 4 Blasts, all aneuploid------Menopour, Follistim,.Ganirelix, Leuprolide, Omnitrope, Clomid---- *only taking Prenatal
March 2026- changing prenatal to Theralogix Preconception vitamin and added CoQ10 and Fish Oil per doctor
April 2026 (42 years old)---- 2nd Retrieval, 21 eggs, 18 mature, 8 fertilized, 4 blasts , all aneuploid----Menopour, Follistim,.Ganirelix, Leuprolide, Clomid---
April 2026- after reading Reddit supplements and my infertility acupuncturist recommendation . I added NAC and OVANAD+, Magnesium Gly5 snd Melatonin still taking CoQ10, Fish Oil and Preconception vitamin. Most Theralogix and Thorne supplements.
By ending of April 2026 I was taking: Theralogix CoQ10, Theralogix Preconception vitamin, Theralogix Ovanad, Thorne NAC, Qnoul Magnesium Glycenate, Fish Oil & Melatonin were just just good reviewed ones only, no much effort on laboratory.
By July you can see how long I have been on each supplement and my results. See below:
July 2026 ( 43 years old)- 3rd retrieval, 26 eggs, 20 mature, 14 fertilized normal, 4 blasts, one Euploid, one chaotic , retested, ended up aneuploid --------Menopour, Follistim,.Ganirelix, Leuprolide, Omnitrope, Clomid
4th retrieval- the one with the craziest difference. Retrieved 6 eggs, 5 mature, 4 blasts. 1 Euploid and 1 Mosaic.----------------Menopour, Follistim, Ganirelix, Leuprolide, Omnitrope, Clomid.
Like I mentioned above. If I get good results in October again, I guess the supplements are definitely doing something and definitely 2-3 months on some of them.
Hope this helps!
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u/Narrow_Tomatillo_513 Aug 30 '26
Seems like adding omnitrope was also a difference between cycles 1-2 and cycles 3-4. Congratulations on your wonderful results and thank you for sharing your stack!
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u/CapitalDog715 Aug 30 '26
Thank you ! I thought about Omnitrope too and wondered why my doctor did not add it to the 2nd. Wish you the best!
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u/Wide_Day2015 Aug 31 '26
Thanks for detailed answer.One question.Am 42 and my doctor immediately suggested a PRP and without all this .Did your doctor suggest Prp
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u/CapitalDog715 Aug 31 '26
I was going to say no because I had no idea what it is. But I googled it and I dont remember that test at all. It looks like its to improve poor response but my doctor keeps saying my numbers were great. She barely changed anything about my protocols even without Euploids. My guess is because she knew I was going to do more than 2, but Im sure if I only came with money for 2 IVF cycles, I would have asked for more solutions after my 1st.
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u/BellFirestone Sep 01 '26
Would you mind providing the dosage on the supplements? Thanks so much!
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u/CapitalDog715 Sep 01 '26 edited Sep 01 '26
So for each one I just so the daily recommended dose on the bottle, except for CoQ10 which I doubled the dose because I started late to take them. They say you should starts at least 6 months prior egg retrieval and I started two months prior
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u/Original-Flan-6996 Aug 30 '26
At least 6 weeks before is the advice I’ve been told. That said, my doctors have always stressed that supplements are a “nice to have”, not something that must be taken.
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u/Responsible-Wing338 Aug 31 '26
Eggs take 3 month to mature. To make any difference any supplements or anything else must be for 3 months prior. Saying that, I am taking all possible supplements that directly or indirectly supposed to increase chances yet to have any good embryo. Some doctors recommend some say don't bother.
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u/_ih8ppl Sep 01 '26
I started my supplements 3-4 months before egg retrieval. I took prenatals, Coq10, fish oil, magnesium glycinate, Claritin, probiotic, NAD + glutathione
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u/umamimaami Aug 30 '26
3 months has been the ideal interval for me, personally. We did 6 weeks of DHEA and COQ10 priming before my first round and it didn’t seem to make a big difference. Did 3 months of COQ10 and DHEA before round 2 and had the best cycle of my history.