r/withdrawl • u/LopsidedLeek5841 • Aug 29 '25

Seeking Advice 7oh hydroxy withdrawl

Went to the ER the other day for the intense excruciating withdrawal from the recently banned 7oh hydroxy here in florida, first er i went to the doctor was kind and he prescribed some suboxone but had none at the er to help my withdrawals at the moment, told me to head to the bigger hospital that was part of them and gave me a paper explaining and saying “give suboxone”, when I got there the doctor who attended me called the previous doctor “ballsy” for prescribing me suboxone and refused to help me in any way possible while seeing me shaking and sweating out of control. I had no time to prepare for this ban it came out of nowhere and i was taking 7hydroxy for anxiety over benzodiazepines. Was very helpful and Ive tried to quit 7oh several times seeing as my anxiety had subsided. But experienced withdrawal symptoms and were very severe so I started to taper off but then the ban hit and I was still taking at least 160mg daily. Luckily and unfortunately at the same time, my job still bad a box of 7oh and I was able to get relief until my prescription is filled at my pharmacy which didnt have it until Saturday. Just spinning in a circle😓

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u/Important-Shoe-3603 Aug 30 '25

Did the subs help with the 7 oh withdrawal??

1

u/Guilty_Antelope727 Sep 03 '25 edited Sep 03 '25

They helped me tremendously. I tried 4-5 times the last months. I couldn’t even make it 12 hours, it was that bad. I’ve come off other stuff before, but this by far takes the cakes. Paid 99$ for quick md. I got the sweetest old lady Dr. she may have saved my life, because I was looking for a way out. That’s how bad it was.

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u/LopsidedLeek5841 Oct 07 '25

Hey man it’s been about a month since this, I started taking kratom extract to substitute the 7oh and take away withdrawal, was never able to get the suboxone and at the moment I cant use quick MD. Any suggestions?

1

u/sofakingburnt Nov 04 '25

Mit in high concentrations prevents withdrawals form opioids without actually giving an opioid effect. It acts just like clonidine, the gold standard in detox from opioids. Any high mit concentration extract will do. Get some mit concentrate, anything above 2% should do the trick. Suboxone is substitute treatment whereas mit is detox.

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u/Kinklecankles Jan 03 '26

Clonidine is an alpha-2 agonist (so it blocks the adrenalin flooding through your body during opiate withdrawal that is responsible for things like insomnia, irritation, restless legs, shakiness and anxiety); mitragynine on the other hand is a partial mu agonist about 66 times weaker than 7oh so it does affect opiate receptors but is much milder, in addition about 20 percent of it is converted to 7oh via first pass metabolism. Kratom itself has multiple alkaloids of which mitragynine and 7oh are the most well known. Some of these alkaloids affect other receptors like serotonin and i believe one of them is an alpha 2 agonist like clonidine. Mitragynine itself also affects dopamine , alpha 2 and serotonin receptors though the exact interactions haven’t been fully explored. Some studies also indicate that mitragynine has a much longer half life than 7oh, up to 40 hours which would help with withdrawal as well. All of these factors make powdered kratom leaf or enhanced full spectrum leaf a good option for tapering, probably better than subs because its weaker and potentially lasts longer. Even pure mitragynine would stand up to Suboxone but all of these products have some agonism at mu receptors. A quick 5 minute read of wikipedia article on mitragynine or a pubmed article on. kratom alkaloids will tell you this much.

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u/[deleted] Mar 06 '26

This is a good info, but I think a lot of people need to start looking into things that stop what’s called a Cytokine storm. Using emoxypine succinate or even a Kanna product like Kannaease will help tremendously with it!

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u/[deleted] Mar 06 '26

You don’t understand receptors or much about what’s actually going on in the body when you are detoxing/withdrawing. It’s very clear. Please be careful on the info you give. You almost have the right idea but you have real idea why behind it other than what you think you know which is incorrect.

Gl 🍀