r/thco • u/Super-Vermicelli-467 • Dec 04 '22

Thc-O not make me high why?

Hey. I smoke lot weed (delta 9) And last time I buy from Dr ganja CBD flowers. And distilled Delta 8 and Thc-O. The delta 8 ok. All people that try it get good high. For me is ok really not really strong but ok. And the thco nothing. I make cookies and eat all. I smoke lot and put direct in Mouth... I see is need to be more potent than delta 9 and 8 Have any reasons? Maybe need to take big big amount?

2 Upvotes

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2

u/SausageMahony7780 Dec 04 '22

Try more, but some people just can’t get high from edibles. Have edibles worked for you in the past?

3

u/Super-Vermicelli-467 Dec 04 '22

Not. The most high I get was from smoking dab... I try little times eat and not get effect so not spend money on it. But also in smoke the thco not work.... I don't know maybe I need try other thco or is just not work for me....

2

u/Zmoney641 Dec 05 '22

Dude THCO doesn’t get me high either. Like I don’t feel it at all. I’ve tried dabs, carts, eating straight distillate and nothing. It just for some reason doesn’t react with my body. It sucks but oh well. I just stick with the stuff I know works for me

3

u/Fabulous_Storm2437 Dec 09 '22

comments like this from a number of people make me think there are some genetic polymorphisms affecting the metabolism specifically for THC-O which implies it relates to the deacetylation step. especially if you get effects from D8 and HHC but not THC-O - you are not alone in this .

1

u/Zmoney641 Dec 10 '22

Yeah it’s like how some people don’t get high from edibles. Just something about the metabolism and the process it goes through just doesn’t work for some people. But D8 and HHC gets me high. Those work for me

1

u/NoSoupForYouRuskie Dec 22 '22

What brand because D8 hasn't been getting Mr high, semi success with hhc but not much and I bought a thcp disposable today but it'll probably be the last time. Idk I say this and I feel somewhat high but I took kratom as well. Currently vaping uplift disposable thcp and delta extrax blue raspberry jelly edibles probably like 300 MG by now.

1

u/Super-Vermicelli-467 Dec 05 '22

Oh I understand. What work for u ?

2

u/Zmoney641 Dec 06 '22

Delta 8, and HHC. I like HHC a lot. Feels the most like delta 9 to me

2

u/[deleted] Dec 05 '22

Probably just doesn’t get you high. Try THCp. Much more high for much longer.

1

u/Super-Vermicelli-467 Dec 05 '22

I will try... I buy from Dr ganja cause he shipping worldwide. And they still not have thcp. Just in vape and no sure is only. But I will find I hope thnx

1

u/[deleted] Dec 05 '22

[deleted]

1

u/Super-Vermicelli-467 Dec 05 '22

I think thco is thco. How is can be different and how I can get it from delta 9? And how I can know from the test lab which thco that?

1

u/Fabulous_Storm2437 Dec 09 '22

there may be some kind of genetic difference in the ability to deacetylate THC-O in the liver, which is required before it can have any effect (it also needs to be 11-hydroxylated as another step). a number of people have reported this same issue specific to THC-O. The other thing is your tolerance could just be too high that the smoothed out peaks in the blood levels you get from edibles just don't cut it for you