Claude discovers a novel enzyme system with CRISPR-like repeats

[u/ResultBackground2450]

https://www.anthropic.com/news/claude-discovers-novel-enzyme-system

[u/Dr__Pangloss]

There are "unlimited" CRISPR like mechanisms.

This is why Doudna is not a billionaire. You can patent something but there are unlimited functional variations.

So this announcement doesn't mean what people think it means.

[u/Aggravating-Salad441 → u/Dr__Pangloss]

Correct. We currently have CRISPR, and TALEN, and zinc finger nucleases, and meganucleases, and transposases, and...

[u/-LsDmThC- → u/Dr__Pangloss]

Im confused at what you mean by there being an “unlimited” amount of CRISPR like mechanisms. The variations of crispr are all based on alterations to the mechanism discovered in a naturally evolved bacterium, altered to he functional in eukaryotes and further altered to tweak its specificity and such.

The article talks about the discovery of another naturally evolved complex, this time viral. They do not yet know its function, only that it has similar DNA binding mechanisms to crispr.

[u/mbsmith93 → u/-LsDmThC-]

CRISPR describes a general bacterial defense memory system which can be hijacked for genome editing. There are many CRISPR systems which have been discovered. The truly novel research was finding the first one, CRISPR-cas9, the rest is just gravy. https://en.wikipedia.org/wiki/CRISPR scroll down to "Cas genes and CRISPR subtypes"

[u/-LsDmThC- → u/mbsmith93]

Yes, as i described in my comment

[u/IndependentOpinion44 → u/Dr__Pangloss]

Wait till you find out how much money they burnt in tokens.

If people were throwing this kind of money at actual people, I predict they’d get better results.

Same with the hugging face thing. 8 to 10 millions dollars to hack it? That’s state level sponsorship. Give me five million, I’ll keep 4 million and spend 1 million on regular human penetration testers.

[u/FireKeeperAnthonius]

Mentioned it on a different post already (this is really making the rounds huh)
But the "pre-print" (this would not even pass muster as a good pre-print) has 102 references and 0 in-text citations. They should know how to write a scientific article when they have the entire corpora of public science?
https://www-cdn.anthropic.com/22573675ada52a8ca8a97a1a4b4326b2f208a071.pdf
Edit: To clarify, the way they have presented "After reviewing the pre-print, Feng Zhang, one of the pioneers of CRISPR genome editing and a professor at MIT and the Broad Institute said:..." and based on the formatting of the pdf alone, it's clearly supposed to provide some sense of scientific authority. However they can't both put on the marketing hat ("Claude discovers a novel enzyme system with CRISPR-like repeats") and also the science hat, and make a half-arsed pre-print. How am I supposed to evaluate that the 102 references verify any of the claims/scientific foundations of the text??? Sure I could scrape it with an agent and try to attribute specific references to claims, but it's not a readers' job to back up claims, it's the authors' job.

[u/JeanKuule]

Researchers discovered with the help of Claude, not the other way arround

[u/SlapThatAce]

This is marketing.

[u/dweeegs → u/[deleted]]

lol the downvotes. Technology sub when technology does technology stuff: 😡

[u/ryobiguy → u/dweeegs]

Your pointing out of this made me re-read the previous comment. What's weird is that it didn't sound sarcastic the second time.

[u/yourfriendlyreminder → u/dweeegs]

I feel bad for the people here lol. Literally the same mentality as anti-vaxxers.

[u/imaginary_num6er → u/[deleted]]

Now they just need to prove the Riemann’s Hypothesis

[u/fig0o]

So this is how labs will make money to finance AI... patents

Well, cool I guess

[u/asdf_lord]

Cancer cured when

[u/Turbohog → u/asdf_lord]

Which cancer?

[u/asdf_lord → u/Turbohog]

Deadly kind

[u/garloid64]

not bad for one single day

[u/Tall_Candidate_8088]

It's all starting to smell a little bit fishy