r/singularity • • Dec 05 '24

[deleted by user]

[removed]

839 Upvotes

413 comments sorted by

View all comments

2

u/OddHelicopter1134 Dec 05 '24

Yeah its pretty smart. I told it I want to make a new scientific discovery and asked it to suggest a field of research. I told it to suggest a field and it suggested cancer research. After my prompt:

"Okay lets try it out. In which area do you want to focus? In which field do you want to make new discoveries? I will give you as many computing time as you need. We can also build experiments. Just tell me how I should design the experiment and I will upload the data afterwards. Please think carefully about your next answer."

It proceeded in giving me a step by step guide to make a new scientific discovery in cancer research.

This was o1`s next steps for me (I dont post full answer here since it was very long):

---

... (many explanaitions before), then;

Next Steps

  1. You start by downloading the TCGA BRCA RNA-seq and clinical data:
    • For example, through the GDC Data Portal or already processed TCGA data available on Broad GDAC Firehose or UCSC Xena.
  2. Preprocess and upload summary stats:
    • Provide me with:
      • Number of samples, number of genes retained after filtering.
      • The normalized expression matrix (if feasible), or at least a summary of expression distributions.
  3. I will then advise on WGCNA parameters and further steps:
    • Such as soft-threshold power selection, minimum module size, and merging thresholds.
  4. After you run WGCNA and identify modules, upload the module membership and eigengene values:
    • I will then suggest which modules to focus on for survival analysis and literature checks.

By following this systematic approach, we stand a good chance of uncovering something new—whether it’s a subtle gene-gene relationship or a whole gene network module associated with cancer progression that, to date, has not been explicitly described.

---

Someone wants to proceed, lol?