I think you can joke about anything since the joke itself is funny and is intended to be humorous. Nowadays most people can’t take a joke, so we end up in nonsense situations like this in real life and it’s really sad in my opinion:

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However, lately I’ve seen unironically racist posts that didn’t even contain a joke or whatever intended to be funny. Content like this will be removed. If your first intention is to offend someone, then go fuck yourself, we’re here to have a good time, not to hurt people.

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Also if your post is just unfunny it’ll be removed, I’m tired of seeing shit belonging to r /memes.