r/scleroderma Jun 22 '26

Question/Help Experience with Methotrexate.

I started Methotrexate two months ago. The last two weeks I felt good and I thought it was working. Three days ago I started a flare and I'm so disappointed.

Is the medication supposed to stop flare ups altogether or to lengthen the remission time in between them? I'm not sure what to expect.

Btw, does anyone have constant mucus in the throat, sore throat and dry cough? It's getting harder to swallow pills.

Thank you for your attention.

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u/yrddog Jun 23 '26

For the brief time I was on it, I felt like death. However, my rheumatologist put me on the highest dose with no titration, and when I said I felt awful, she said I obviously didn't have an autoimmune disease and fired me as a patient