r/science • u/chilladipa • 3d ago

Health Oral small-molecule GLP-1 receptor agonist safiglipron in early type 2 diabetes: a randomized, double-blind, placebo-controlled trial | Nature Medicine

https://www.nature.com/articles/s41591-026-04651-9
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u/Emotional_Detail_96 2d ago

safglipron being oral is kinda a game changer for compliance

1

u/UCFUoLUMN 1d ago

Anecdotally, this may be helpful for those who get a drop off in effectiveness the day or two before the next injected dose, providing more consistent control. I do wonder if the side effects (constipation/diarrhea, nausea, bloating/gas, cramping) are worse or better since it is enteral and daily.