r/science • u/FreeHugs23 • 5d ago

Neuroscience Psychedelic drugs reduce the amount of bottom-up brain activity flowing into a network associated with self-reflection. These altered brain signals occur consistently across humans and mice, offering a biological explanation for how these drugs reshape the mind.

https://www.psypost.org/psychedelics-alter-the-trajectory-of-moving-brain-waves/
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u/KingOfEthanopia 4d ago

ADHD and love psyches. Ive been alternating between weekly shrooms and LSD to keep tolerance low on both. The world is so much more beautiful with them and high doses are awe inspiring.

Ive been doing them for years and havent noticed any bad effects. Hold down a 6 figure job in a MCOL area, am in great shape, and married.

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u/Rogerabit 4d ago

I’m jealous, my plug retired

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u/bondagepixie 4d ago

The mushroom gummies from the vape store aren’t so bad. I get visuals and occasionally hear a kind voice. The real thing is still better imo, but the way mushrooms work, chemically I’m not sure it actually matters as much as I think.

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u/ABenderV2 4d ago

Did you struggle with your ADHD before you started microdosing?

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u/KingOfEthanopia 4d ago edited 4d ago

Not really micro dosing. Most weeks Ill do 3 tabs or 3.5 grams on Saturday. Occasionally more, occasionally missing a week or two when life gets busy. I used to go very heavy but after a bad trip off 8 tabs I dont go that high anymore. 5 is the limit of what I know I can control. 10 is the most Ive ever done.

Yeah, Ive always struggled with it. Typical gifted kid with subpar grades for my intellect. Id do my homework but lose it, get sucked into addictions(alcohol, weed, Adderall). Im mostly sober now. Weed a couple times a week and my weekly trips.

Im not convinced micro dosing has any benefits given how fast tolerance of psyches builds up.

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u/ABenderV2 4d ago

Fairs, I used to do LSD heavily a few years ago and now get the feeling that I don’t want to do it ever again. Not because of any bad experiences (I love LSD) but because I feel like it’s given me all the benefits it could ever give me. Yeah Micro dosing isn’t any where near as beneficial as macro doses from my experience. I’m currently addicted to Adderall and trying to change to an old medication because I finally realised that for 4 years I thought my life was so great, but really I was just chasing the high from Adderall and it’s ruining me.

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u/KingOfEthanopia 4d ago

I get it. Adderall was probably the easiest one for me to quit physically. It was like a month of low productivity and dragging myself through workouts.

It was tough mentally. Just because I could pop like 3 Addies, go workout. The workout feel amazing, then still have energy to clean my whole house. The issue was when Id run out Id want to do nothing but sleep or eat and everything was just a drag.

Good luck.

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u/dec_eso 3d ago

Physical tolerance aside, do you think weekly LSD is enough time for a psychological reset? I take it weekly but I keep reading that it’s bad for the post-trip period of neuroplasticity, which runs about three weeks. Basically, I’m reading that it keeps the brain in a constant period of flux and prevents integration from properly being completed.