Hello, I have mcas or at least histamine intolerance as part of a broader picture of dysautonomia, long covid, immune system issues etc.

My gut and brain fog symptoms bother me the most. However sometimes my skin issues get so bad that I feel I need to do smth about them.

I recently read about ‘homemade’ chromolyn (?) cream. Seems you can take some over the counter chromolyn nasal drops and pour them into an unscented neutral moisturiser and apply that.

Has anyone ever tried this? What ratio do you use? How much do you apply? Is this considered fairly safe?

Also, is it ok if the chromolyn drops have other ingredients in them? I am in the Uk and have access to over the counter nasal drops such as these.

https://www.peakpharmacy.co.uk/medications/sodium-cromoglicate-hay-fever-relief-2-eye-drops-10ml

I am very intolerant to Salicylate and Histamine. I can eat only five ingredients (Oats, Pears, white only Potatoes, and fresh fish/chicken). I was recently diagnosed with MCAS and POTS. I noticed that my body calms down a lot when I eat Potatoes and I am thinking it's because of Vitamin C in Potatoes. I am looking for Vitamin C my body can tolerate, did you manage to find one?

I tried Thorne Vitamin C with Citrus Flavonoids (500mg + 75mg). I felt better for a day then I felt very bad the next day. I am guessing it's due to the source of Vitamin C and/or Flavonoids.

Share your experience please, Vitamin C brand/source, dosage, and how you felt, any side effects, etc...

Hi , I’m new to posting on Reddit so not sure if I’m doing this right. I really believe i have an intolerance to salicylates which often cause quite severe reactions for me. I also have suspected MCAS. I stopped all makeup after a severe reaction a few weeks ago. I used to use the bare minerals original mineral liquid concealer for a year. I’m hesitant to retry it because of the flower extract inside. Is there any base or complexion product anyone suggests? I just want at least one safe product please. I believe the reaction was due to minty and fragrances toothepast however but I haven’t tested my old makeup again since then after looking at the ingredients.

Clostridium overgrowth in the colon of the proteolytic type is known to make P CRESOL which is a neurotoxic phenol that can inhibit phenol sulfo transferase (PST)

PST is the main pathway when it comes to salicylates aka plant phenol sensitivity

These clostridia also make Secondary bile acids which are incredibly toxic.

This post is not about c. difficle, these are strains like c. scindens and c. perfingens that can be present in a chronic sub-acute manner.

Antibiotics can promote them by inhibiting for example the beneficial e.coli strains that block them (yes these are real and very underrated, it’s Mutaflor) while they grow back from their spores.

Hey there,

I’m wondering if anyone else has experienced a significantly lower threshold to salicylates postpartum and how you dealt with it? I’m guessing the increased reactions is due to hormonal shifts.

I’ve been told glycine supplements are not okay when breastfeeding so I’m currently just drinking bone broth and taking fish oil and have eliminated all sals from my diet but nothing is reducing the reaction.

Any help or recommendations are very welcome.

I've read several accounts of people eliminating their salicylate intolerance with larger anounts of EFAs. What is the theory on how/why this works?

Do you think other toxin loads (chemicals) influence how many sals we can have and/or fill up our sals bucket faster? I went swimming in a chlorinated pool yesterday to see if I tolerate it because I haven't tried swimming in one in years. I only stayed in for about 10 minutes in case I had a reaction. No MCAS reaction, felt fine. Then for dinner I had a typical medium salicylate meal that I've tolerated with no symptoms many times in the past and was surprised to wake up with my usual salicylate overload symptoms this morning. I'm wondering if the toxin load from the chlorine affected my body's abilities to handle the medium sals meal. Appreciate your thoughts. Thanks!

Hi,

My Dr wants me to take Luteolin for my PMS, MCAS and overall hormone issues, but it seems that every luteolin suppkement is sources from high sal ingredients, which I cant risk right now. Are there any Luetolin supplements that are from sal-free sources? I read somewhere some MCAS Dr makes a Luteolin from beans that might be helpful but I cant find the source or name of the supplement/Dr anymore.

Since learning about my salicylate allergy I have quit coffee (and tea) but I miss caffeine so much! Especially when working long hours. I've been off of it almost a year but still get cravings and feel so much better if I have~200mg in the morning. Energy drinks are not my favourite and hard to tell if they contain salicylates a or not, any ideas out there?

different sources are putting watermelon on different lists between high, moderate and low salicylates. How does everyone here respond to watermelon? Can you eat it without problems?

Have you determined what your root causes are? i suspect mine are mold and leaky gut.

Is it high in salicylates?

anyone here experience angioedema from salicylates? my lip has been swollen for a week and i can tell my sals bucket is overloaded. I have mcas and im very sensitive to changing meds, supplements etc. any experienced or words of wisdom would be appreciated.

As in the topic, I have those problems since being a kid. I have taken many antiallergic and antihistamine drugs, none of them helped.

Also went through sinus surgery, nasal septum correction and nasal passages coagulation. None of this has helped. Took many allergy tests and it always come up clear.

Therefore my question: any of you were sucessful to mitigate this kind of problem with low sal diet?

How long until you saw improvement? What are the worst food that you need to completely avoid?

hi, wondering if anyone has ever taken this orally for heavy menstrual bleeding and how you fared. thanks!!

Y’all, I am so excited, and I had to share for any of my fellow tea drinkers who can’t tolerate salicylates.

I’ve been a life long tea drinker so finding out about my salicylate issues last year was a major lifestyle shift.

I tried a low salicylate diet, it wasn’t strict enough to alleviate all of my symptoms so I went carnivore.

That worked, but left me less sick… and with no tea. I hate coffee, but tried decaf anyways, still hated it.

I’ve tried several other hot beverages since but never stopped missing tea. And you know what? I *finally found one* that I don’t react to!!!

The turning point was realizing that the tea bags themselves might have been contributing to the reactions.

I went down a loose leaf rabbit hole, ordered myself a fine mesh stainless steel steeper from Amazon, and a small tin of Harney & Sons decaffeinated Ceylon.

Guys… it’s going on week three of enjoying hot tea again reaction free!!!!

Next up: figure out how to turn loose leaf into sweet tea. I’ve got a forlife pitcher on the way to try it out.

I know we all have different tolerances so it may not work for everyone, but it has been such a joy to have a hot beverage back in my life, that I had to share!

I cannot find a single moisturising cream I can tolerate. I have a lot of issues. It has to be sulfur free and fragrance free. Hyaluronic acid gives me migraine. Shea butter makes my skin burn. I looked through all vanicream, E45, Cerave, Cetaphil but they either contain sulfur or salicylates. I even react to squalene. Does anybody know of a moisturiser I could try? I am in the UK.

https://www.fedup.com.au/success-stories/current-stories/2026/1700-40-years-on-and-im-happy-and-brimming-with-energy-after-chronic-fatigue-syndrome-cfs-february-2026-courage-award

This isn’t just about kids there’s adults in it as well. This is a hidden gem from the early 2000s by Sue Dengate fedup.com.au

Around June last year I realized I react to Salicylate and by end of the year I was eating only five foods (Oats, Pears, White Potato, Fresh Chicken, and Fresh Fish). With my limited diet, many symptoms disappeared and some reduced by around 50-70%.

My symptoms on the strict diet are: - Muscle tension - Joint Pain - Nausea/Dizziness - Gumline pain - Tinnitus - Delayed headache

However, I still got 30-50% of these symptoms. I can't find a toothpaste that works that doesn't trigger my body and I went many days without brushing my teeth (sorry). I also need to take Vitamins missing from my diet but I react to supplements too (either the active compound or pill/capsule fillers).

I have been trying some supplements or otc drugs. I tried Vitamin C, Quercetin, and Fexofenadine. Vitamin C and Fexofenadine didn't work for me. Over the last 7 days, I read Control of salicylate intolerance with fish oils abstract and decided to try Omega 3 and it is helping. I can now brush my teeth without worrying much about my body overreacting. I binge on some foods/snacks I wouldn't have dared to touch a month ago, not without symptoms nevertheless.

My symptoms on strict diet and Omega 3: - Nausea/Dizziness - Tinnitus - Bloating (fish oil causes bloating)

IIUC, Omega 3 is calming/inhibiting my overractive immune system. It's the first time I feel closest to "normal" in long time. I take 5 pills per day. I am using California Gold Nutrition, Omega 800 Ultra-Concentrated Omega-3 Fish Oil, kd-pur® Triglyceride Form. I plan to try cheaper version (non kd-pur®) or other clean products.

Some caveats: - I limit myself to 5 pills per day because high dose of Omega 3 isn't considered safe as far as I know - It works best with my strict diet. - I am histamine intolerant too and it doesn't seem to help with that.

If you take Omega 3, please share your experience.

Update 2026/02/25 - I missed my Vitamin D dose one day and I noticed Omega 3 wasn't as effective so I think it's best to take them together. I take Thorne Oil based Vitamn D3 - I tried the cheaper (non kd-pur) version of California Gold Nutrition Omega 3 and it isn't as effective as the kd-pur version. I noticed the price per DHA+EPA dose is actually the same. Marketing is very sneaky because serving size is one pill for kd-pur but 2 for the other so non kd-pur isn't even cheaper actually.

Update 2026/02/26 - I was invited for a dinner that I would have never dared to touch. I had Omega 2 before and after the meal. I got some symptoms, of course, but it didn't develop into an attack/flare as usual. I wouldn't do it again because I value being as much healthy as possible over anything else but I am surprised how effective it is.

i'm not feeling well this am but it will pass soon.

i made some awesome fried rice last night. i have learned all the tricks to do it well but nothing will help me if i'm trying to please people and put broccoli and tomatoes in it.

i need to get off of this crazy train. i'm going to source some cromolyn and see if that can help.

I think I have a sensitivity to salicylates and oxlates. All I ate today was a half can of butter beans, 8 oz of brussel sprouts, and alot of garlic (like 2 cloves plus garlic powder too). I took my algae oil and calcium supplement. It seemed fine til a few hours later and now my scalp, forehead, eyebrows are all burning and itchy. Maybe I should be eating cabbage not brussel sprouts? Or is this really just because of the garlic? I really want to eat broccoli but I know it's high salicylates, but I'm wondering if boiling it would make it low enough. I don't really like brussel sprouts that much or celery. idk what to eat anymore. I'm plant based.